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US 10,774,033 B2Granted
Methods of synthesis of (1R, 2R, 5R)-5-amino-2-methylcyclohexanol hydrochloride and intermediates useful therein
AssigneeCelgene Corporation
InventorsTerrence Joseph Connolly, Hon-Wah Man, Periyandi Nagarajan, Chinnapillai Rajendiran, Jasti Venkateswarlu
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Abstract
Provided herein are methods and intermediates for making (1R,2R,5R)-5-amino-2-methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated with the JNK pathway.
Claims3
A method for preparing a compound of formula (7),
- the method comprising contacting a compound of formula (6),
- with (+)-dibenzoyl-D-tartaric acid monohydrate in a solvent.
A compound of formula (7),
Dependencies are inferred from the claim text.