# US 10,768,193 B2 · Automatic analyzer > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,768,193 B2 - Document ID: US10768193B2 - Status: Granted - Kind: B2 - Application number: 15/747,446 - Filed: 2016-07-13 - Published: 2018-07-26 - Granted: 2020-09-08 - Earliest claimed: 2015-07-29 - Assignees: Hitachi High-Tech Corporation - Applicants: Hitachi High-Technologies Corporation - Inventors: Masaru Miyazaki; Takamichi Mori; Kouhei Nonaka - Web page: https://patentgrep.com/patent/US10768193B2 ## CPC - G01N 35/1079: {with means for piercing stoppers or septums} - B01L 3/52: {Containers specially adapted for storing or dispensing a reagent (B01L3/02 takes precedence; storing or dispensing test elements G01N33/4875; automated reagent dispensing G01N35/1002)} - G01N 35/00584: {Control arrangements for automatic analysers} - G01N 35/02: using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations {(G01N35/0098 and G01N35/0099 take precedence)} - G01N 35/025: {having a carousel or turntable for reaction cells or cuvettes} - G01N 35/1002: {Reagent dispensers} - B01L 3/00: Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers - B01L 2200/16: Reagents, handling or storing thereof - B01L 2300/044: pierceable, e.g. films, membranes - G01N 35/1095: {for supplying the samples to flow-through analysers (for a specific analyser see relevant groups, e.g. under G01N15/00, G01N21/00, G01N27/00, G01N30/00, H01J49/00)} - G01N 2035/0097: {monitoring reactions as a function of time} - G01N 2035/0443: {for reagents} - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE ## Abstract A needle for forming a cut in a reagent bottle lid is shaped such that an expansion portion which pushes and opens a cut and a piercing portion which forms the cut are integrated with each other. Consequently, only a single operation for moving the needle downwardly will form a cut using the needle and expand the cut using the expansion portion. Further, the smaller diameter of the expansion portion than the diameter of a circumscribed circle of a cross section of the piercing portion but equal to or greater than the diameter of the reagent probe can form cuts uniformly. ## Claims ### Claim 1 An automatic analyzer, comprising: a sample probe configured to suck a specimen and discharge the specimen into a reaction vessel; a reagent probe configured to suck a reagent and discharge the reagent into the reaction vessel; a photometer configured to analyze a mixture of the specimen and the reagent in the reaction vessel; a reagent disk configured to hold a reagent bottle storing the reagent; a needle configured to form a cut in a lid of the reagent bottle; a lid opening mechanism configured to drive the needle; and a controller configured to control the lid opening mechanism, wherein the needle comprises: a piercing portion including a plurality of blades for forming the cut in the lid of the reagent bottle and a cylindrical expansion portion configured to push into and open the cut, wherein the plurality of blades are disposed at vertices of a regular polygon as viewed from a distal end of the piercing portion, wherein the cylindrical expansion portion has a diameter smaller than a maximum diameter of a circumscribed circle passing through all vertices of the regular polygon of the plurality of blades of the piercing portion and has the diameter that is equal to or larger than a maximum diameter of the reagent probe within a range within which the reagent probe is inserted into the reagent bottle before the reagent probe sucks the reagent, wherein the cylindrical expansion portion includes a stepped portion, wherein the piercing portion includes a tapered portion extending from a vertex of the regular polygon of a blade of the plurality of blades toward the stepped portion of the cylindrical expansion portion, wherein an axial length of the cylindrical expansion portion is greater than an axial length of the piercing portion, and wherein the controller is programmed to control the lid opening mechanism so that the needle is inserted to the expansion portion after the cut is formed in the lid of the reagent bottle by the piercing portion. ### Claim 2 (depends on 1) The automatic analyzer according to claim 1, wherein the controller is further programmed to control the lid opening mechanism to insert the expansion portion of the needle to a location of the lid in which the cut is formed by a single downwardly, moving operation thereby to push and open the lid member between locations through which the plurality of blades pass. ### Claim 3 (depends on 1) The automatic analyzer according to claim 1, wherein the diameter of the cylindrical expansion portion is greater than the maximum diameter of the reagent probe within the range within which the reagent probe is inserted into the reagent bottle before the reagent probe sucks the reagent. ### Claim 4 (depends on 1) The automatic analyzer according to claim 1, wherein the piercing portion has a polygonal pyramid shape and the sides of the polygonal pyramids correspond to the plurality of blades. ### Claim 5 (depends on 1) The automatic analyzer according to claim 1, wherein the plurality of blades are blades extending from the center to the outer side as viewed from the distal end of the piercing portion. ### Claim 6 (depends on 1) The automatic analyzer according to claim 1, wherein the reagent probe sucks the reagent stored in the reagent bottle through the cut opened by pushing of the expansion portion. ### Claim 7 (depends on 1) The automatic analyzer according to claim 1, further comprising a reagent bottle transport mechanism configured to transport the reagent bottle in which the cut has been formed by the needle to the reagent disk. ### Claim 8 An automatic analyzer, comprising: a sample probe configured to suck a specimen and discharge the specimen into a reaction vessel; a reagent probe configured to suck a reagent and discharge the reagent into the reaction vessel; a photometer configured to analyze a mixture of the specimen and the reagent in the reaction vessel; a reagent disk configured to hold a reagent bottle storing the reagent; a needle configured to form a cut in a lid of the reagent bottle; a lid opening mechanism configured to drive the needle; and a controller configured to control the lid opening mechanism, wherein the needle comprises: a piercing portion including a plurality of blades for forming the cut in the lid of the reagent bottle, and a cylindrical expansion portion configured to push into and open the cut, wherein the cylindrical expansion portion has a diameter which is smaller than a maximum diameter of a circumscribed circle of the plurality of blades of the piercing portion and is equal to or greater than a maximum diameter within a range within which the reagent probe is inserted into the reagent bottle to a position at which the reagent probe sucks the reagent, wherein the cylindrical expansion portion includes a stepped portion, wherein the piercing portion includes a tapered portion extending from a vertex of a blade of the plurality of blades toward the stepped portion of the cylindrical expansion portion, wherein an axial length of the cylindrical expansion portion is greater than an axial length of the piercing portion, and wherein the controller controls the lid opening mechanism so that the needle inserted to the expansion portion after the cut is formed in the lid of the reagent bottle by the piercing portion. ### Claim 9 (depends on 1) The automatic analyzer according to claim 1, wherein the stepped portion of the cylindrical expansion portion includes a flat surface facing downward toward the plurality of blades and perpendicular to an axial dimension of the needle.