A device for purifying a gaseous fluid mixture to produce a concentrated neon gas, starting from a mixture comprising neon, said device comprising, in a cold box housing a cryogenic purification circuit comprising, in series, at least one unit for purifying the mixture by cryogenic adsorption at a temperature between 65K and 100K, then a unit for cooling the fluid mixture to a temperature between 25 and 65 K and then a unit for cryogenic distillation of the fluid mixture to produce a concentrated liquid at the outlet of the cryogenic distillation unit, characterized in that the unit for cooling the fluid mixture to a temperature between 25 and 65 K comprises at least one cryocooler that extracts thermal power from the mixture via a heat exchanger, the at least one cryocooler comprising at least one cryocooler of the Gifford McMahon type or a pulsed gas tube or a cryocooler of the Stirling type.