# US 10,765,717 B2 · Detoxifying composition containing new green extract as active ingredient

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- Number: US 10,765,717 B2
- Document ID: US10765717B2
- Status: Granted
- Kind: B2
- Application number: 16/254,712
- Filed: 2019-01-23
- Published: 2019-05-23
- Granted: 2020-09-08
- Earliest claimed: 2014-11-07
- Assignees: Famenity Co., Ltd.
- Applicants: Famenity Co., Ltd.
- Inventors: Yoo Hun Noh; Young Ja Kim; Jeong Min Lee
- Web page: https://patentgrep.com/patent/US10765717B2

## CPC

- A61K 36/31: Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61K 36/28: Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61P 39/02: Antidotes
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

The present invention relates to a detoxifying composition containing a new green extract, which is a medicinal herb, as an active ingredient. Thus, toxicities in the human body can be efficiently removed without side effects by activating an enzyme necessary for detoxification.

## Claims

### Claim 1

A preparation method of a detoxifying food with new green extract,
(a) preparing a new green;
(b) sorting and grinding the new green;
(c) carrying out an extraction to extract an extract from the ground new green repeatedly one to ten times by using a solvent;
(d) filtering the extract by a filter cloth to produce a filtrate; and
(e) concentrating the filtrate under vacuum to produce a new green extract,
wherein, in step (c), the solvent is one of water with a volume amount (v/w %) which is 1 to 25 times the weight of the ground new green, an alcohol having 1 to 4 carbon atoms, and a mixed solvent thereof; the extraction is performed at 0 to 120° C. for 1 hour to 10 days; and the extraction is performed by cold brew extraction, hot water extraction, ultrasonic extraction, reflux cooling extraction, or heated extraction, and
the new green extract is capable of activating phase II and phase III in a detoxification process as an active ingredient.

### Claim 2

A preparation method of a detoxifying food with a complex extract of new green and thistle,
(a1) preparing a new green and a thistle;
(b1) sorting and grinding the new green;
(c1) carrying out a first extraction to extract a first extract from the ground new green repeatedly one to ten times by using a first solvent;
(d1) filtering the first extract by a first filter cloth to produce a new green filtrate;
(e1) concentrating the new green filtrate under vacuum to produce a new green extract,
wherein, in step (c1), the first solvent is one of water with a volume amount (v/w %) which is 1 to 25 times the weight of the ground new green, an alcohol having 1 to 4 carbon atoms, and a mixed solvent thereof; wherein the first extraction is performed at 0 to 120° C. for 1 hour to 10 days; and the first extraction is performed by cold brew extraction, hot water extraction, ultrasonic extraction, reflux cooling extraction, or heated extraction;
(a2) sorting and grinding the thistle;
(b2) carrying out a second extraction to extract a second extract from the ground thistle repeatedly one to ten times by using a second solvent;
(c2) filtering the second extract by a second filter cloth to produce a thistle filtrate;
(d2) concentrating the thistle filtrate under vacuum to produce a thistle extract,
wherein, in step (b2), the second solvent is one of water with a volume amount (v/w %) which is 1 to 25 times the weight of the ground thistle, an alcohol having 1 to 4 carbon atoms, or a mixed solvent thereof; the second extraction is performed at 0 to 120° C. for 1 hour to 10 days; and the second extraction is performed by cold brew extraction, hot water extraction, ultrasonic extraction, reflux cooling extraction, or heated extraction; and
(g) mixing the new green extract with the thistle extract to produce a complex extract,
wherein the complex extract is capable of activating phase II and phase III in a detoxification process as an active ingredient.

### Claim 3 (depends on 1)

The method of claim 1, further comprising, (f) mixing the new green extract with a dextrin.

### Claim 4 (depends on 2)

The method of claim 2, further comprising, (f) mixing the new green extract with a first dextrin and mixing the thistle extract with a second dextrin between step (d2) and step (g).

### Claim 5 (depends on 1)

The method of claim 1, further comprising (f) lyophilizing the new green extract.

### Claim 6 (depends on 2)

The method of claim 2, further comprising, (f) lyophilizing the new green extract and the thistle extract between step (d2) and step (g).

### Claim 7 (depends on 3)

The method of claim 3, the ratio of the new green extract and the dextrin is 1:1.

### Claim 8 (depends on 4)

The method of claim 4, the ratio of the new green extract and the first dextrin is 1:1 and the ratio of the thistle extract and the second dextrin is 1:1.

### Claim 9 (depends on 1)

The method of claim 1, wherein the phase II is activated by an increase in glutathione S-transferase, quinone reductase, and UDP-glucuronosyl transferase.

### Claim 10 (depends on 2)

The method of claim 2, wherein the phase II is activated by an increase in glutathione S-transferase, quinone reductase, and UDP-glucuronosyl transferase.