# US 10,765,707 B2 · Honey-based gel composition > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,765,707 B2 - Document ID: US10765707B2 - Status: Granted - Kind: B2 - Application number: 14/942,721 - Filed: 2015-11-16 - Published: 2016-03-10 - Granted: 2020-09-08 - Earliest claimed: 2010-04-07 - Assignees: Derma Sciences, Inc. - Applicants: Derma Sciences, Inc. - Inventors: Fatma Bilge Thompson - Web page: https://patentgrep.com/patent/US10765707B2 ## CPC - A61K 35/644: Beeswax; Propolis; Royal jelly; Honey - A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)} - A61K 9/06: Ointments; Bases therefor; {Other semi-solid forms, e.g. creams, sticks, gels (composition of ointments, creams or gels A61K47/00)} - A61K 31/23: of acids having a carboxyl group bound to a chain of seven or more carbon atoms - A61K 31/7028: Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages - A61L 26/0057: {Ingredients of undetermined constitution or reaction products thereof} - A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract A honey based composition is described. The composition includes a mixture of honey, a short chain fatty alcohol and a fatty ester or wax. The composition has applications for use in wound dressings and in one embodiment may be a gel. The composition has a higher than expected storage stability, remaining stable for many weeks when held at elevated temperatures and retains all of the other desirable characteristics including anti-microbial activity. ## Claims ### Claim 1 A composition for treating a patient wherein the composition consists of: a. 80 wt % honey; b. 5 wt % caprylyl capryl glucoside; and c. 15 wt % of myristyl myristate; wherein the composition has been subjected to a sterilization effective dosage of radiation and is storage stable for a time period of at least 24 hours at 40° C. ### Claim 2 (depends on 1) The composition as claimed in claim 1, wherein the composition is stable for at least 8 days when stored at 40° C. ### Claim 3 (depends on 1) The composition as claimed in claim 1, wherein the composition is stable for at least 21 days when stored at 40° C. ### Claim 4 (depends on 1) The composition as claimed in claim 1, wherein the composition is stable for at least 15 weeks when stored at 40° C. ### Claim 5 (depends on 1) The composition as claimed in claim 1, wherein the composition is a gel. ### Claim 6 (depends on 1) The composition as claimed in claim 1, wherein the composition has a viscosity of 50×103 to 600×103 cPs at 25° C. ### Claim 7 (depends on 1) The composition as claimed in claim 1, wherein the myristyl myristate has a melting point of about 37° C. or greater. ### Claim 8 (depends on 1) The composition as claimed in claim 1, wherein the honey has both peroxide and non-peroxide activity. ### Claim 9 (depends on 1) The composition as claimed in claim 1, wherein the pH is between 3.0 and 6.0 for the duration of storage. ### Claim 10 (depends on 1) The composition as claimed in claim 1, wherein the pH is between 4.0 and 5.0 for the duration of storage. ### Claim 11 (depends on 1) The composition as claimed in claim 1, wherein the sterilization effective dosage of radiation is greater than 10 kGy. ### Claim 12 (depends on 1) The composition as claimed in claim 1, wherein the sterilization effective dosage of radiation is greater than 20 kGy. ### Claim 13 (depends on 1) The composition as claimed in claim 1, wherein the sterilization effective dosage of radiation is 25 kGy. ### Claim 14 (depends on 1) The composition as claimed in claim 1, wherein the composition has an antibacterial activity>10% phenol equivalent or>10 unique manuka factor activity over the shelf life. ### Claim 15 (depends on 1) The composition as claimed in claim 1, wherein the honey is manuka honey. ### Claim 16 (depends on 15) The composition as claimed in claim 15, wherein the composition is stable for at least 8 days when stored at 40° C. ### Claim 17 (depends on 15) The composition as claimed in claim 15, wherein the composition is stable for at least 21 days when stored at 40° C. ### Claim 18 (depends on 15) The composition as claimed in claim 15, wherein the composition is stable for at least 15 weeks when stored at 40° C. ### Claim 19 (depends on 15) The composition as claimed in claim 15, wherein the composition has a viscosity of 50×103 to 600×103 cPs at 25° C. ### Claim 20 (depends on 15) The composition as claimed in claim 15, wherein the pH is between 4.0 and 5.0 for the duration of storage.