# US 10,765,657 B2 · Selamectin for treatment of sea lice infestations

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- Number: US 10,765,657 B2
- Document ID: US10765657B2
- Status: Granted
- Kind: B2
- Application number: 14/367,977
- Filed: 2014-02-26
- Published: 2015-12-24
- Granted: 2020-09-08
- Earliest claimed: 2013-02-26
- Assignees: Zoetis Services LLC
- Applicants: Zoetis Services LLC
- Inventors: John Adam Wendt; David Jose Asper; Stacy Ross
- Web page: https://patentgrep.com/patent/US10765657B2

## CPC

- A61K 31/352: condensed with carbocyclic rings, e.g. methantheline {(cannabinoids A61K31/658)}
- A23K 20/10: Organic substances
- A23K 20/147: Polymeric derivatives, e.g. peptides or proteins
- A23K 20/158: Fatty acids; Fats; Products containing oils or fats
- A23K 20/163: Sugars; Polysaccharides
- A23K 50/80: for aquatic animals, e.g. fish, crustaceans or molluscs
- A61K 9/0019: {Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00)}
- A61K 31/7048: having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin {, digitoxin or digoxin}
- A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61K 47/36: Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K 47/38: Cellulose; Derivatives thereof
- A61K 47/44: Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin (synthetic glycerides, e.g. medium-chain triglycerides, A61K47/14)
- A61P 33/00: Antiparasitic agents
- A61P 33/14: Ectoparasiticides, e.g. scabicides
- Y02A 40/818: Alternative feeds for fish, e.g. in aquacultures
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23K: FODDER
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE

## Abstract

The invention describes a method for treating a parasitic infection or infestation, particularly sea lice, in a fish by administering an effective amount of selamectin.

## Claims

### Claim 1

A method for treating a parasitic infection or infestation from sea lice in a fish, the method comprising orally administering to said fish a therapeutically effective amount of about 50-150 μg/kg/day of selamectin with a dietary fish feed admixed with selamectin.

### Claim 2 (depends on 1)

The method of claim 1, wherein the sea lice are of the genera Lepeophtheirus and Caligus.

### Claim 3 (depends on 2)

The method of claim 2, wherein the sea lice is at least one of Lepeophtheirus salmonis, Caligus celmensi, Caligus curtus, Caligus dussumieri, Caligus elongates, Caligus longicaudatus, Caligus rogercresseyi or Caligus stromii.

### Claim 4 (depends on 1)

The method of claim 1 wherein the fish is a farmed fish and is selected from the group consisting of carp, tuna, tilapia, cod, halibut, trout, and salmon.

### Claim 5 (depends on 4)

The method of claim 4 wherein the fish feed is further admixed with an oil that is selected from a fish oil or vegetable oil.