# US 10,765,603 B2 · Medical container

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- Number: US 10,765,603 B2
- Document ID: US10765603B2
- Status: Granted
- Kind: B2
- Application number: 15/021,663
- Filed: 2015-03-06
- Published: 2016-08-04
- Granted: 2020-09-08
- Earliest claimed: 2014-03-13
- Assignees: Naturan International Co., Ltd.
- Applicants: Naturan International Co., Ltd.
- Inventors: Shigeki Matsumoto; Katuhiro Arai; Tsuyoshi Shiga
- Web page: https://patentgrep.com/patent/US10765603B2

## CPC

- A61J 1/1468: {Containers characterised by specific material properties}
- A61J 1/10: Bag-type containers
- A61J 1/1412: {Containers with closing means, e.g. caps}
- B65D 85/00: Containers, packaging elements or packages, specially adapted for particular articles or materials (bundles of articles held together by packaging elements for convenience of storage or transport B65D71/00)
- C01B 3/061: by reaction of water with metal oxides
- C01B 3/10: by reaction of water vapour with metals
- B32B 2439/80: Medical packaging
- Y02E 60/36: Hydrogen production from non-carbon containing sources, e.g. by water electrolysis
- A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- B65D: CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- C01B: NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; {METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C}
- B32B: LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- Y02E: REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION

## Abstract

A hydrogen-generating substance that reacts with moisture (liquid water or water vapor) in a medical substance or moisture in air introduced into a medical container is kneaded into an exterior sheet 40 of the medical container that encloses the medical substance therein. The medical container can be a bag-shaped medical container, a tube-shaped medical container, a medical container with a sealing fastener or the like. The medical substance containing moisture can be blood, an injection solution, a drug solution, a nutrient solution, a replenishment solution (an infusion solution), an instillation solution or the like. A solid preparation is preferably enclosed within the medical container with the sealing fastener. For example, the hydrogen-generating substance to be kneaded can be metal magnesium and is preferably fine-powdered ceramics obtained by firing the mixture of a hydrogen-generating substance and a mineral substance such as calcium.

## Claims

### Claim 1

A medical container which can be opened and closed with a sealing fastener, and which is configured to enclose a solid preparation therein, the medical container comprising:
an exterior sheet comprising a first layer sheet and a second layer sheet, the first layer sheet and the second layer sheet overlapping with one another in a direction from an inner surface side of the exterior sheet to an outer surface side of the exterior sheet,
wherein the first layer sheet comprises an inner sheet and an adjacent outer sheet,
wherein the inner sheet is configured to absorb water, permit passage of water vapor and not permit passage of liquid water,
wherein a hydrogen-generating substance for generating hydrogen gas by reacting with moisture is kneaded into the outer sheet, and the hydrogen-generating substance generates hydrogen when moisture that passes through the inner-sheet contacts the hydrogen-generating substance in the outer sheet, and
wherein the second layer sheet is a barrier layer that comprises aluminum foil.

### Claim 2 (depends on 1)

The medical container of claim 1,
wherein said exterior sheet is formed by attaching the outer sheet to an inner surface of the second layer sheet.

### Claim 3 (depends on 2)

The medical container of claim 2, wherein said outer sheet is attached to only part of said second sheet.

### Claim 4 (depends on 1)

The medical container of claim 1, wherein the hydrogen-generating substance is kneaded in the form of fine-powdered ceramics obtained by firing a mixture of the hydrogen-generating substance and a mineral substance.

### Claim 5 (depends on 4)

The medical container of claim 4,
wherein said hydrogen-generating substance is metal magnesium,
and wherein said mineral substance is calcium.

### Claim 6

A medical container which can be opened and closed with a sealing fastener, and which is configured to enclose a solid preparation therein, the medical container comprising:
an exterior sheet comprising a first layer sheet and a second layer sheet, the first layer sheet and the second layer sheet overlapping with one another in a direction from an inner surface side of the exterior sheet to an outer surface side of the exterior sheet,
wherein the first layer sheet is configured to absorb water, permit passage of water vapor and not permit passage of liquid water, and wherein a hydrogen-generating substance for generating hydrogen gas by reacting with moisture in air introduced into the medical container when the sealing fastener is opened, is kneaded into the first layer sheet, and the hydrogen-generating substance generates hydrogen when moisture that passes through the first layer sheet contacts the hydrogen-generating substance in the first layer sheet, and
wherein the second layer sheet is a barrier layer that comprises aluminum foil.

### Claim 7 (depends on 6)

The medical container of claim 6, wherein the hydrogen-generating substance is kneaded in the form of fine-powdered ceramics obtained by firing a mixture of the hydrogen-generating substance and a mineral substance.

### Claim 8 (depends on 7)

The medical container of claim 7, wherein said hydrogen-generating substance is metal magnesium, and wherein said mineral substance is calcium.

### Claim 9 (depends on 1)

The medical container of claim 1, wherein the generated hydrogen gas reacts with oxygen in the container to prevent or reduce oxidation of the solid preparation therein.

### Claim 10 (depends on 7)

The medical container of claim 7, wherein the generated hydrogen gas reacts with oxygen in the container to prevent or reduce oxidation of the solid preparation therein.
