# US 10,765,509 B2 · Intraocular devices and methods for correction of aphakia, restoration of accommodation, and treatment of glaucoma

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- Number: US 10,765,509 B2
- Document ID: US10765509B2
- Status: Granted
- Kind: B2
- Application number: 15/770,067
- Filed: 2016-10-20
- Published: 2018-11-01
- Granted: 2020-09-08
- Earliest claimed: 2015-10-21
- Assignees: The Regents of the University of Colorado, a body corporate
- Applicants: The Regents of the University of Colorado, a body corporate
- Inventors: Jeffrey Olson; Michael Erlanger
- Web page: https://patentgrep.com/patent/US10765509B2

## CPC

- A61F 2/1605: {Anterior chamber lenses for use in addition to the natural lenses of the eyes, e.g. iris fixated, iris floating}
- A61F 2/16: Intraocular lenses
- A61F 2/1629: {for changing longitudinal position, i.e. along the visual axis when implanted}
- A61F 9/00781: {Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002)}
- G02C 7/04: Contact lenses for the eyes (disinfection or sterilisation of contact lenses A61L12/00)
- A61F 2002/1682: {having mechanical force transfer mechanism to the lens, e.g. for accommodating lenses}
- A61F 2002/1689: {having plate-haptics}
- A61F 2220/0091: connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type
- A61F 2250/0067: Means for introducing or releasing pharmaceutical products into the body
- A61F 2250/0098: radio-opaque, e.g. radio-opaque markers
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- G02C: SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES (trial frames for testing the eyes A61B3/04; goggles or eyeshields not having the same features as spectacles A61F9/00)

## Abstract

A device according to the present disclosure comprises an intraocular prosthetic. In some embodiments, the device comprises a lens portion and a plurality of arms that radiate outward from the lens portion. The lens portion can comprise a central ring used to hold an intraocular lens. Each arm can comprise a foot plate which allows the device to push out distally against a ciliary body. Among other things, an intraocular device according to the present disclosure can be useful in correction of aphakia, restoration of accommodation, and treatment of glaucoma.

## Claims

### Claim 1

An intraocular device comprising:
a lens portion configured to support a separate and distinct lens; and
a plurality of arms radiating distally from the lens portion, wherein the plurality of arms are integral with the lens portion,
wherein each of the plurality of arms comprises a strut and a foot plate,
wherein the foot plate is curved to conform with a ciliary body, and
wherein the intraocular device further comprises a hinge lever extending between the strut and the footplate of each of the plurality of arms.

### Claim 2 (depends on 1)

The intraocular device of claim 1 wherein the lens portion comprises a shelf, a recess, a bar, or a clip configured to support the separate and distinct lens.

### Claim 3 (depends on 1)

The intraocular device of claim 1 wherein the hinge lever is configured to facilitate translation of force from along a first plane to along a second plane non-parallel with the first plane.

### Claim 4 (depends on 1)

The intraocular device of claim 1, wherein the plurality of arms are evenly spaced about, and extend radially outward from, a periphery of the lens portion such that gaps are defined between adjacent arms of the plurality of arms.

### Claim 5 (depends on 1)

The intraocular device of claim 1 wherein the strut is linear, wherein the strut is coplanar with the lens portion.

### Claim 6 (depends on 5)

The intraocular device of claim 5 wherein the foot plate is concave in an anterior direction.

### Claim 7 (depends on 6)

The intraocular device of claim 6 wherein contraction of the ciliary body exerts a force on each of the plurality of arms in a first direction along a first plane, and wherein the force displaces the lens portion in a second direction along a second plane.

### Claim 8 (depends on 7)

The intraocular device of claim 7 wherein the first plane is normal to the second plane.

### Claim 9 (depends on 6)

The intraocular device of claim 6 wherein the foot plate is configured to contact the ciliary body to provide a decrease in the production of aqueous fluid.

### Claim 10 (depends on 9)

The intraocular device of claim 9 wherein the foot plate comprises a distal edge, wherein the decrease in the production of aqueous fluid, in response to the distal edge of the foot plate contacting the ciliary body, lowers an intraocular pressure in an eye comprising the ciliary body.

### Claim 11

A method for treating an ocular condition comprising:
providing an intraocular device, wherein the intraocular device comprises a lens portion, and a plurality of arms radiating distally from the lens portion, wherein the plurality of arms are integral with the lens portion, wherein each of the plurality of arms comprises a strut and a foot plate, and wherein the foot plate is curved to conform with a ciliary body;
placing the intraocular device in a subject exhibiting presbyopia or glaucoma; and
securing a separate and distinct lens to the lens portion of the intraocular device;
wherein placing the intraocular device in the subject comprises positioning the foot plate such that it contacts the ciliary body to provide a decrease in the production of aqueous fluid.

### Claim 12 (depends on 11)

The method for treating an ocular condition of claim 11 wherein contraction of the ciliary body exerts a force on each of the plurality of arms in a first plane, and wherein the force displaces the lens portion in a second plane and thereby treats presbyopia.

### Claim 13 (depends on 12)

The method for treating an ocular condition of claim 12 wherein the first plane is normal to the second plane.

### Claim 14 (depends on 11)

The method for treating an ocular condition of claim 11, wherein placing the intraocular device comprises lowering an intraocular pressure in an eye comprising the ciliary body.

### Claim 15 (depends on 1)

The intraocular device of claim 1, wherein a radius of curvature of the curved foot plate is between 0.2 mm and 2.0 mm.

### Claim 16 (depends on 1)

The intraocular device of claim 1, wherein an arc of the curved foot plate is between about 45 degrees to about 90 degrees.

### Claim 17

An intraocular device comprising:
a lens portion configured to support a separate and distinct lens; and
a plurality of arms radiating distally from the lens portion, wherein the plurality of arms are integral with the lens portion,
wherein each of the plurality of arms comprises a strut and a foot plate,
wherein the foot plate is curved to conform with a ciliary body, and
wherein a radius of curvature of the curved foot plate is between 0.2 mm and 2.0 mm.
