# US 10,765,504 B2 · Adjustable vascular graft for custom inner diameter reduction and related methods > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,765,504 B2 - Document ID: US10765504B2 - Status: Granted - Kind: B2 - Application number: 16/111,850 - Filed: 2018-08-24 - Published: 2019-06-06 - Granted: 2020-09-08 - Earliest claimed: 2017-12-01 - Assignees: C. R. Bard, Inc. - Applicants: C.R. Bard, Inc. - Inventors: Keith Harris; Kevin Boyle - Web page: https://patentgrep.com/patent/US10765504B2 ## CPC - A61F 2/06: Blood vessels - A61F 2/07: Stent-grafts - A61L 27/16: obtained by reactions only involving carbon-to-carbon unsaturated bonds - A61L 27/56: Porous materials, {e.g. foams or sponges} - B29C 55/22: of tubes {(B29C61/08 takes precedence)} - A61F 2220/0075: sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable - A61F 2230/001: Figure-8-shaped, e.g. hourglass-shaped - A61F 2240/001: Designing or manufacturing processes - A61F 2240/002: Designing or making customized prostheses - A61F 2250/001: for adjusting a diameter - A61F 2250/0036: differing in thickness - A61F 2250/0098: radio-opaque, e.g. radio-opaque markers - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - B29C: SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING (making preforms B29B11/00; making laminated products by combining previously unconnected layers which become one product whose layers will remain together B32B37/00 - B32B41/00) ## Abstract An adjustable vascular graft with a user-customizable reduced inner diameter is provided. The graft includes a flexible tubular body having open ends and a plurality of receivers in a sidewall thereof, which may be arranged in two circumferentially spaced rows of receivers. The receivers may take the form of ringlets, eyelets, loops, or holes, which may be provided in a reinforced region of the graft sidewall, and which may be radiopaque. A suture passes through the plurality of receivers, the suture having first and second free ends capable of being pulled, and which suture may also be radiopaque. Tensioning or tightening the first and second ends of the suture reduces an inner diameter of the corresponding portion of the tubular body of the graft, thereby allowing for the custom reduced inner diameter and a resulting flow restriction to be provided. Related methods are also disclosed. ## Claims ### Claim 1 A prosthetic medical device having an adjustable configuration from a first diameter to a second diameter smaller than the first diameter along an adjustable length, wherein the second diameter is maintained in vivo following implantation in a body to create a flow restricted passage in the prosthetic medical device, the prosthetic medical device comprising: a tubular graft having open ends and a continuous outer wall circumscribing a lumen along a longitudinal axis, the outer wall having the first diameter at each of a proximal portion, a distal portion, and a middle portion, the middle portion having the adjustable length, the outer wall including at least two rows of receivers spaced apart in a circumferential direction along the adjustable length; and a suture passing through the rows of receivers to form a crossing pattern or a zig-zag pattern, the suture having a first free end and a second free end, wherein movement of the first free end and the second free end away from the rows of receivers transitions the adjustable length from a first configuration with the first diameter to a second configuration with the second diameter. ### Claim 2 (depends on 1) The prosthetic medical device of claim 1, wherein the at least two rows of receivers comprise a plurality of pairs of receivers, wherein each of the pairs of receivers is spaced in an axial direction. ### Claim 3 (depends on 2) The prosthetic medical device of claim 2, wherein each of the pairs of receivers is aligned in the circumferential direction. ### Claim 4 (depends on 2) The prosthetic medical device of claim 2, wherein each of the pairs of receivers is staggered in the axial direction. ### Claim 5 (depends on 1) The prosthetic medical device of claim 1, wherein the first free end of the suture extends from an outermost receiver at a first end portion of the adjustable length, and wherein the second free end of the suture extends from an outermost receiver at a second end portion of the adjustable length. ### Claim 6 (depends on 1) The prosthetic medical device of claim 1, wherein the first free end and the second free end of the suture extend from respective outermost receivers at an end of the at least two rows of receivers. ### Claim 7 (depends on 1) The prosthetic medical device of claim 1, wherein the at least two rows of receivers include a first row of receivers and a second row of receivers, the first row of receivers spaced farther from the second row of receivers in a loosened condition of the suture and spaced closer to the second row of receivers in a tightened condition of the suture. ### Claim 8 (depends on 1) The prosthetic medical device of claim 1, wherein the rows of receivers are provided on an intermediate portion of the tubular grail to create an hourglass shape when the adjustable length is transitioned to the second diameter. ### Claim 9 (depends on 1) The prosthetic medical device of claim 1, wherein each receiver in the rows of receivers comprises an eyelet. ### Claim 10 (depends on 1) The prosthetic medical device of claim 1, wherein each receiver in the rows of receivers is provided by a projection from the outer wall. ### Claim 11 (depends on 10) The prosthetic medical device of claim 10, wherein each projection is created by a ringlet connected to the outer wall. ### Claim 12 (depends on 10) The prosthetic medical device of claim 10, wherein the projection comprises a loop formed by a second suture anchored to the outer wall of the tubular graft. ### Claim 13 (depends on 1) The prosthetic medical device of claim 1, wherein the rows of receivers are provided by a beading attached to the outer wall of the tubular graft. ### Claim 14 (depends on 1) The prosthetic medical device of claim 1, wherein the rows of receivers comprise holes formed in a reinforced region of the tubular graft. ### Claim 15 (depends on 14) The prosthetic medical device of claim 14, wherein the reinforced region is a thickened region of the outer wall of the tubular graft. ### Claim 16 (depends on 14) The prosthetic medical device of claim 14, wherein the reinforced region is a sintered region of the outer wall of the tubular graft. ### Claim 17 (depends on 1) The prosthetic medical device of claim 1, wherein the suture comprises a radiopaque material. ### Claim 18 (depends on 1) The prosthetic medical device of claim 1, wherein the rows of receivers comprise a radiopaque material. ### Claim 19 (depends on 1) The prosthetic medical device of claim 1, wherein the tubular graft comprises expanded polytetrafluoroethylene.