# US 10,765,490 B2 · Therapeutic tooth bud ablation

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- Number: US 10,765,490 B2
- Document ID: US10765490B2
- Status: Granted
- Kind: B2
- Application number: 16/036,904
- Filed: 2018-07-16
- Published: 2018-11-08
- Granted: 2020-09-08
- Earliest claimed: 2013-03-15
- Assignees: TriAgenics, Inc.
- Applicants: Triagenics, Inc.
- Inventors: Leigh E. Colby
- Web page: https://patentgrep.com/patent/US10765490B2

## CPC

- A61C 1/082: {Positioning or guiding, e.g. of drills}
- A61B 6/03: Computed tomography [CT]
- A61B 18/06: caused by chemical reaction {, e.g. moxaburners}
- A61B 18/082: {Probes or electrodes therefor}
- A61B 18/1477: {Needle-like probes}
- A61B 18/148: {having a short, rigid shaft for accessing the inner body transcutaneously, e.g. for neurosurgery or arthroscopy}
- A61B 18/1485: {having a short rigid shaft for accessing the inner body through natural openings}
- A61B 18/1815: {using microwaves}
- A61B 34/10: Computer-aided planning, simulation or modelling of surgical operations
- A61B 34/20: Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B 90/11: with guides for needles or instruments, e.g. arcuate slides or ball joints
- A61C 1/084: {of implanting tools}
- A61C 3/00: Dental tools or instruments (implanting tools A61C8/00; tools for fastening artificial teeth A61C13/12; visual inspection devices, e.g. dental mirrors, A61B1/24)
- A61C 3/14: Dentists' forceps or the like for extracting teeth
- A61C 5/42: Files for root canals; Handgrips or guiding means therefor
- A61C 8/0089: {Implanting tools or instruments}
- A61C 13/0004: {Computer-assisted sizing or machining of dental prostheses}
- A61B 18/02: by cooling, e.g. cryogenic techniques
- A61B 18/1402: {Probes for open surgery}
- A61B 34/25: {User interfaces for surgical systems}
- A61B 2017/00115: {with audible or visual output}
- A61B 2018/00178: {Electrical connectors}
- A61B 2018/00297: {Means for providing haptic feedback}
- A61B 2018/00321: {Head or parts thereof}
- A61B 2018/00327: {Ear, nose or throat}
- A61B 2018/00565: {Bone}
- A61B 2018/00577: {Ablation}
- A61B 2018/00613: {Irreversible electroporation}
- A61B 2018/00642: {with feedback, i.e. closed loop control}
- A61B 2018/0066: {without feedback, i.e. open loop control}
- A61B 2018/00702: {Power or energy}
- A61B 2018/00708: {switching the power on or off}
- A61B 2018/00714: {Temperature}
- A61B 2018/00785: {Reflected power}
- A61B 2018/00797: {measured by multiple temperature sensors}
- A61B 2018/00875: {Resistance or impedance}
- A61B 2018/00898: {Alarms or notifications created in response to an abnormal condition}
- A61B 2018/00994: {combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound}
- A61B 2018/0293: {using an instrument interstitially inserted into the body, e.g. needle}
- A61B 2018/1869: {with an instrument interstitially inserted into the body, e.g. needles}
- A61B 2018/2005: {with beam delivery through an interstitially insertable device, e.g. needle}
- A61B 2034/104: {Modelling the effect of the tool, e.g. the effect of an implanted prosthesis or for predicting the effect of ablation or burring}
- A61B 2034/105: {Modelling of the patient, e.g. for ligaments or bones}
- A61B 2034/107: {Visualisation of planned trajectories or target regions}
- A61B 2034/108: {Computer aided selection or customisation of medical implants or cutting guides}
- A61B 2090/034: {abutting on parts of the device itself}
- A61B 2090/036: {abutting on tissue or skin}
- A61C 9/0006: {Impression trays}
- A61C 9/004: {Means or methods for taking digitized impressions}
- A61N 2007/025: {interstitial}
- Y10T 29/49826: Assembling or joining
- A61C: DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE (non-driven toothbrushes A46B; {tongue scrapers A61B17/24;} preparations for dentistry A61K6/00; preparations for cleaning the teeth or mouth A61K8/00, A61Q11/00)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

Ablation probe tips (108, 148, 320, 360) and physical and virtual stents (110) for use in tooth bud ablation procedures that result in tooth agenesis as well as tooth bud ablation methods are described herein.

## Claims

### Claim 1

An ablation probe tip, said ablation probe tip for use in a tooth bud ablation procedure that results in tooth agenesis, said ablation probe tip for use with a stent, said ablation probe tip for use with an ablation probe unit, said ablation probe tip comprising:
(a) said ablation probe tip having a shaft, said shaft having an insertion end for inserting into a tooth bud and a connection end for connecting said ablation probe tip to said ablation probe unit;
(b) said ablation probe tip having a center of ablation;
(c) said ablation probe tip being guidable at a pre-defined angle when used in conjunction with said stent;
(d) said ablation probe tip being depth limited to a pre-defined depth;
(e) said ablation probe tip having a shaft inner conductor, shaft insulation surrounding said shaft inner conductor, a shaft outer shield surrounding said shaft insulation, a window defined in said shaft outer shield, a shaft outer cover surrounding said shaft outer shield and said window, and a reflector positioned between said window and said insertion end, said center of ablation positioned in said shaft inner conductor surrounded by said window; and
(f) said center of ablation being a focal area from which ablation means radiates through said window;
wherein said center of ablation is within said tooth bud when said ablation probe tip is guided at said pre-defined angle to said pre-defined depth.

### Claim 2 (depends on 1)

The ablation probe tip of claim 1, said center of ablation positioned between said insertion end and said connection end.

### Claim 3 (depends on 1)

The ablation probe tip of claim 1, at least part of said ablation means is reflected from said reflector.

### Claim 4 (depends on 1)

The ablation probe tip of claim 1, said reflector selected from a group consisting of:
(a) a deposited reflector;
(b) a deposited metal reflector;
(c) a soldered reflector; and
(d) an electroplated reflector.

### Claim 5 (depends on 1)

The ablation probe tip of claim 1, said window being a gap window.

### Claim 6 (depends on 1)

The ablation probe tip of claim 1, said window being an air gap window.

### Claim 7 (depends on 1)

The ablation probe tip of claim 1, said ablation probe tip is for at least partially ablating at least one tooth bud without ablating surrounding tissue.

### Claim 8 (depends on 1)

The ablation probe tip of claim 1, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth.

### Claim 9 (depends on 1)

The ablation probe tip of claim 1, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth, said at least one stop indicator being provided by the physical prevention of further progression of said ablation probe tip provided by the interaction of mechanical stop structure of said ablation probe tip and mechanical stop structure of said stent.

### Claim 10 (depends on 1)

The ablation probe tip of claim 1, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth, said at least one stop indicator being provided by a virtual stop marking on said display.

### Claim 11 (depends on 1)

The ablation probe tip of claim 1, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth, said at least one stop indicator being provided by an indicator selected from the group consisting of:
(a) a visual indicator;
(b) an audible indicator;
(c) a tactile indicator; and
(d) a combination of at least two indicators selected from (a)-(c).

### Claim 12

An ablation probe tip, said ablation probe tip for use in a tooth bud ablation procedure that results in tooth agenesis, said ablation probe tip for use with an ablation probe unit, said ablation probe tip comprising:
(a) said ablation probe tip having a shaft, said shaft having an insertion end for inserting into a tooth bud and a connection end for connecting said ablation probe tip to said ablation probe unit;
(b) said ablation probe tip having a center of ablation between said insertion end and said connection end; and
(c) said ablation probe tip having a shaft inner conductor, shaft insulation surrounding said shaft inner conductor, a shaft outer shield surrounding said shaft insulation, a window defined in said shaft outer shield, a shaft outer cover surrounding said shaft outer shield and said window, and a reflector positioned between said window and said insertion end, said center of ablation positioned in said shaft inner conductor surrounded by said window;
wherein said center of ablation is a focal area from which ablation means radiates through said window, said center of ablation being positionable within said tooth bud.

### Claim 13 (depends on 12)

The ablation probe tip of claim 12, said center of ablation positioned between said insertion end and said connection end.

### Claim 14 (depends on 12)

The ablation probe tip of claim 12, at least part of said ablation means is reflected from said reflector.

### Claim 15 (depends on 12)

The ablation probe tip of claim 12, said reflector selected from a group consisting of:
(a) a deposited reflector;
(b) a deposited metal reflector;
(c) a soldered reflector; and
(d) an electroplated reflector.

### Claim 16 (depends on 12)

The ablation probe tip of claim 12, said window being a gap window.

### Claim 17 (depends on 12)

The ablation probe tip of claim 12, said window being an air gap window.

### Claim 18 (depends on 12)

The ablation probe tip of claim 12, said ablation probe tip is for at least partially ablating at least one tooth bud without ablating surrounding tissue.

### Claim 19 (depends on 12)

The ablation probe tip of claim 12, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth.

### Claim 20 (depends on 12)

The ablation probe tip of claim 12, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth, said at least one stop indicator being provided by the physical prevention of further progression of said ablation probe tip provided by the interaction of mechanical stop structure of said ablation probe tip and mechanical stop structure of said stent.

### Claim 21 (depends on 12)

The ablation probe tip of claim 12, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth, said at least one stop indicator being provided by a virtual stop marking on said display.

### Claim 22 (depends on 12)

The ablation probe tip of claim 12, said ablation probe tip being depth limited by at least one stop indicator to a pre-defined depth, said at least one stop indicator being provided by an indicator selected from the group consisting of:
(a) a visual indicator;
(b) an audible indicator;
(c) a tactile indicator; and
(d) a combination of at least two indicators selected from (a)-(c).