# US 10,765,324 B2 · Photoacoustic image generation apparatus and insert

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- Number: US 10,765,324 B2
- Document ID: US10765324B2
- Status: Granted
- Kind: B2
- Application number: 15/855,487
- Filed: 2017-12-27
- Published: 2018-05-17
- Granted: 2020-09-08
- Earliest claimed: 2015-06-30
- Assignees: FUJIFILM Corporation
- Applicants: FUJIFILM Corporation
- Inventors: Kaku Irisawa
- Web page: https://patentgrep.com/patent/US10765324B2

## CPC

- A61B 5/0095: {by applying light and detecting acoustic waves, i.e. photoacoustic measurements}
- A61B 8/0841: {for locating instruments}
- A61B 5/6848: {Needles}
- A61B 8/13: Tomography (A61B8/10, A61B8/12 take precedence)
- A61B 8/5246: {combining images from the same or different imaging techniques, e.g. color Doppler and B-mode}
- A61B 17/3417: {Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating (syringe needles A61M5/32; dilators A61M29/00)}
- A61B 8/4416: {related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions}
- A61B 2576/00: Medical imaging apparatus involving image processing or analysis (A61B1/00009, A61B6/52 and A61B8/52 take precedence)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

There are provided a photoacoustic image generation apparatus and an insert that separately acquire both positional information and surrounding environment information of the insert. A puncture needle is at least partially inserted into a subject. An optical fiber guides light with a first wavelength and light with a second wavelength which are incident while being switched. The light guided by the optical fiber is emitted from a light emitting portion. A light absorption member absorbs the light with the first wavelength emitted from the light emitting portion, generates photoacoustic waves, and transmits the light with the second wavelength emitted from the light emitting portion.

## Claims

### Claim 1

An insert that is at least partially inserted into a subject, comprising:
a light guide member that guides light with a first wavelength and light with a second wavelength different from the first wavelength which are incident while being switched;
a light emitting portion from which the light guided by the light guide member is emitted; and
a light absorption member that absorbs the light with the first wavelength emitted from the light emitting portion, generates photoacoustic waves, and transmits the light with the second wavelength emitted from the light emitting portion;
wherein:
the insert is a puncture needle having an inner cavity;
the insert further includes a hollow tube in which the light guide member is accommodated;
the puncture needle includes an inner needle and an outer needle;
the inner needle includes the hollow tube; and
the inner needle seals at least a portion of the inner cavity.

### Claim 2 (depends on 1)

The insert according to claim 1, wherein the light absorption member covers at least a part of the light emitting portion.

### Claim 3 (depends on 1)

The insert according to claim 1, wherein the light absorption member includes a light absorber that absorbs the light with the first wavelength and transmits the light with the second wavelength and a resin including the light absorber.

### Claim 4 (depends on 1)

The insert according to claim 1, wherein:
the light absorption member functions as a fixing member that fixes the light guide member to an inner wall of the inner cavity.

### Claim 5 (depends on 1)

The insert according to claim 1, further comprising a transparent resin that transmits at least the light with the second wavelength,
wherein the light absorption member is covered with the transparent resin.

### Claim 6 (depends on 5)

The insert according to claim 5, wherein the insert has an inner cavity; and
the light guide member and the light absorption member are fixed to an inner wall of the inner cavity by the transparent resin.

### Claim 7 (depends on 1)

The insert according to claim 1, wherein the light absorption member functions as a fixing member that fixes the light guide member to an inner wall of the hollow tube.

### Claim 8 (depends on 1)

The insert according to claim 1, further comprising a transparent resin that transmits at least the light with the second wavelength,
wherein the light guide member and the light absorption member are fixed to an inner wall of the hollow tube by the transparent resin.

### Claim 9 (depends on 1)

The insert according to claim 1, further comprising a phosphor that absorbs the light with the second wavelength emitted from the light emitting portion, and converts the light with the second wavelength into light with a third wavelength different from the first wavelength and the second wavelength.

### Claim 10 (depends on 1)

The insert according to claim 1, further comprising an optical connector that detachably connects the light guide member and an optical fiber which guides the light with the first wavelength and the light with the second wavelength emitted from a light source.

### Claim 11

A photoacoustic image generation apparatus comprising:
a first light source that emits light with a first wavelength;
a second light source that emits light with a second wavelength different from the first wavelength;
an insert that is at least partially inserted into a subject and comprises a light guide member that guides the light with the first wavelength and the light with the second wavelength which are incident while being switched, a light emitting portion from which the light guided by the light guide member is emitted, and a light absorption member that absorbs the light with the first wavelength emitted from the light emitting portion, generates photoacoustic waves, and transmits the light with the second wavelength emitted from the light emitting portion;
acoustic wave detection section for detecting first photoacoustic waves which are generated by the absorption of the light with the first wavelength by the light absorption member and second photoacoustic waves which are generated in the subject due to the light emitted from the light emitting portion; and
photoacoustic image generation section for generating a first photoacoustic image on the basis of the first photoacoustic waves and generating a second photoacoustic image on the basis of the second photoacoustic waves.

### Claim 12 (depends on 11)

The photoacoustic image generation apparatus according to claim 11, wherein the second photoacoustic waves are generated by the absorption of the light with the second wavelength transmitted through the light absorption member by the subject.

### Claim 13 (depends on 11)

The photoacoustic image generation apparatus according to claim 11, wherein
the insert further includes a phosphor that absorbs the light with the second wavelength emitted from the light emitting portion, and converts the light with the second wavelength into light with a third wavelength different from the first wavelength and the second wavelength; and
the second photoacoustic waves are generated by the absorption of the light with the third wavelength emitted from the phosphor by the subject.

### Claim 14 (depends on 11)

The photoacoustic image generation apparatus according to claim 11, wherein:
the acoustic wave detection section further detects reflected acoustic waves with respect to acoustic waves transmitted to the subject; and
the photoacoustic image generation apparatus further comprises reflected acoustic image generation section for generating a reflected acoustic image on the basis of the reflected acoustic waves.

### Claim 15 (depends on 14)

The photoacoustic image generation apparatus according to claim 14, further comprising:
image combination section for combining at least one of the first photoacoustic image or the second photoacoustic image and the reflected acoustic image.
