Graphene-based nanopore and nanostructure devices and methods for macromolecular analysis
AssigneeThe Trustees of the University of Pennsylvania
InventorsMarija Drndic, Ken Healy, Meni Wanunu, Christopher Ali Merchant, Matthew Puster, Kimberly Elizabeth Venta
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Abstract
Provided are graphene-based nanopore and nanostructure devices, which devices may include an insulating layer disposed atop the graphene, which can be in a planar shape or nanostructured into a ribbon or other shapes, containing a single graphene layer or several layers. Graphene layers and nanostructures can be placed nearby horizontally or stacked vertically. Also provided are related methods of fabricating and processing such devices and also methods of using such devices in macromolecular analysis.
Claims23
A device, comprising:
- a first graphene sheet being characterized as having a bowtie profile and having a narrowed region that defines a width in a direction,
- the narrowed region bridging first and second regions of the first graphene sheet, each of the first and second regions defining a width in the direction that is greater than the width of the narrowed region in the direction, the narrowed region having a thickness and further comprising at least one pore extending through the thickness of the narrowed region, the pore being contained within the narrowed region,
- the pore characterized by a cross-sectional dimension in the range of from about 0.1 nm to about 100 nm,
- the cross-sectional dimension of the pore being less than the width of the narrowed region;
- and
- a membrane contacting the first graphene sheet,
- the membrane having an aperture in register with the pore of the first graphene sheet.
Dependencies are inferred from the claim text.