Peptides and uses thereof
AssigneesFundació Centre De Regulació GenóMica (Crg), Institució Catalana De Recerca I Estudis AvançAts
InventorsBernhard Paetzold, Maria Lluch Senar, Luis Serrano Pubul
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Abstract
The invention provides a series of peptide signals which, when linked to a polypeptide of interest (POI), ensure that said polypeptide is secreted in high yields by a host cell such as Mycoplasma pneumoniae. The invention also provides fusion proteins tagged with said peptide signals, the nucleic acid sequences coding for them, host cells comprising said tagged fusion proteins and a variety of uses of the fusion proteins and the host cells.
Claims4
A nucleotide sequence encoding a peptide consisting of a sequence having at least 90% homology with, and having the same length as, a sequence selected from the group consisting of:
- SEQ ID NO:
- 1;
- SEQ ID NO:
- 2;
- SEQ ID NO:
- 3;
- SEQ ID NO:
- 4;
- SEQ ID NO:
- 5;
- and SEQ ID NO:
- 6, wherein said nucleotide sequence is operably linked to a heterologous promoter.
Dependencies are inferred from the claim text.