Back to results
US 10,745,346 B2Granted
Agonists of protein tyrosine phosphatase SHP-1
OwnerKuen-Feng Chen, Chung-Wai Shiauinventors
Life of this patent
Estimating the term…
Abstract
Some novel compounds are provided in this disclosure. These novel compounds have potential SHP-1 agonist activity for being used in treating cancer.
Claims6
A compound having a chemical structure below:
- wherein n is 0 or 1;
- X is N or C—R1;
- R1 is H or Cl;
- R2 and R3 are H, a halide or an alkyl group independently;
- Ar is an unsubstituted or substituted phenylene group or a naphthalenylene group, wherein the substituted phenylene group is
- and the naphthalenylene group is
- R4 is H, a halide or an alkyl group;
- R5 is H, a halide, an alkyl group, an alkoxyl group or a hydroxyl group;
- R6 is H or a hydroxyl group;
- R7 is a substituted phenyl group, a substituted
- wherein the substituted phenyl group is selected from one of
- and
- wherein the substituted
- is selected from one of
- and
- wherein, when R7 is
- R2, R3, R4, R5, and R6 are not H at a same time.
14 more elements
Dependencies are inferred from the claim text.