Device and methods for tuning a skeletal muscle

A method of tuning a lower limb skeletal muscle in a subject in need thereof comprising the steps of:

• (a) securing a device to a subject's foot, whereby said device comprises a foot securing means, a support member operably attached to said securing means;
• an outsole;
• an anterior protuberance and a posterior protuberance;
• (b) calibrating the center of pressure (COP) with which the foot contacts the ground by positioning said posterior protuberance, positioning said anterior protuberance, or both, wherein said calibrating the COP is:
• (1) increasing the lower limb skeletal muscle activity by positioning the COP in a direction away from the anatomical location of the lower limb skeletal muscle;
• or (2) reducing the lower limb skeletal muscle activity by positioning the COP in a direction closer to the anatomical position of the lower limb skeletal muscle;
• and
• (c) fixing said posterior protuberance and said anterior protuberance to said support member in a fixed position, thereby tuning a lower limb skeletal muscle in a subject in need thereof.