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US 10,744,328 B2Granted
System for generating and applying waveform shapes for treating neurological disorders optimized for energy efficiency
AssigneeDuke University
InventorsWarren M. Grill, Amorn Wongsarnpigoon
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Abstract
Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency.
Claims7
A system for creating and applying a stimulation waveform optimized for energy efficiency comprising:
- a population of parent stimulation waveforms;
- a genetic algorithm (GA) for generating a population of offspring stimulation waveforms by mating the population of parent stimulation waveforms,
- a computational model of extracellular stimulation of a mammalian myelinated axon, being operative for assessing the fitness of individual offspring stimulation waveforms generated by the genetic algorithm in terms of energy efficiency and selecting as a new population of the parent stimulation waveforms the current offspring stimulation waveforms having the highest energy efficiency values, the selection terminating when predetermined termination criteria is met to provide an optimized stimulation waveform, and
- an implantable pulse generator being operable to apply the optimized stimulation waveform.
1 more element
Dependencies are inferred from the claim text.