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US 10,744,261 B2Granted
System and method of a biosensor for detection of vasodilation
AssigneeSanmina Corporation
InventorsRobert Steven Newberry, Matthew Rodencal
Life of this patent
Estimating the term…
Abstract
An optical circuit detects PPG signals reflected from skin tissue at one or more different wavelengths. A processing circuit integrated in the biosensor or in communication with the biosensor processes the PPG signals to obtain a level of vasodilation or a period of vasodilation. The processing circuit may determine a circulation level using a phase offset between the PPG signals and/or a correlation value between the PPG signals.
Claims22
A device, comprising:
- an optical circuit configured to:
- detect photoplethysmography (PPG) signals over a monitoring period, wherein the PPG signals include a first spectral response obtained from light reflected around a first wavelength from skin tissue of a patient and a second spectral response obtained from light reflected around a second wavelength from the skin tissue of the patient, wherein the first wavelength penetrates the skin tissue of the patient at a different depth than the second wavelength;
- a processing device configured to:
- determine a correlation between a first pulse shape from the first spectral response and a second pulse shape from the second spectral response;
- determine a ratio (R) value using the first spectral response and the second spectral response over a monitoring period, wherein the R value is determined using a ratio of an alternating current (AC) component of the first spectral response and an AC component of the second spectral response;
- determine a change in the R value obtained using the first spectral response and the second spectral response during the monitoring period;
- and
- determine one or more of:
- a vasodilation period or a level of vasodilation using the correlation between the first pulse shape and the second pulse shape and the change in the R value.
6 more elements
A biosensor, comprising:
- an optical circuit configured to:
- detect a first photoplethysmography (PPG) signal reflected around a first wavelength from skin tissue of a patient and a second PPG signal reflected around a second wavelength from the skin tissue of the patient;
- a processing circuit configured to:
- determine a correlation value between the first and second PPG signals, wherein the correlation value depends on a difference in pulse shape between the first and second PPG signals;
- compare the correlation value in pulse shape to a predetermined normal range of correlation values;
- determine a ratio (R) value using the first spectral response and the second spectral response over a monitoring period, wherein the R value is determined using a ratio of an alternating current (AC) component of the first spectral response and an AC component of the second spectral;
- and
- determine an abnormal circulation level when the correlation value and the R value is outside the predetermined normal range, wherein the abnormal circulation level indicates a blood circulation problem in the tissue.
5 more elements
A device, comprising:
- a photoplethysmography (PPG) circuit configured to:
- obtain a first PPG signal around a first wavelength reflected from skin tissue of a patient and a second PPG signal around a second wavelength reflected from the skin tissue of the patient;
- a processing device configured to:
- obtain a measure of similarity in pulse shape between the first and second PPG signals;
- compare the measure of similarity in pulse shape to a predetermined normal range;
- determine a ratio (R) value using the first spectral response and the second spectral response over a monitoring period, wherein the R value is determined using a ratio of an alternating current (AC) component of the first spectral response and an AC component of the second spectral response;
- determine a concentration level of nitric oxide (NO) using the R value;
- and
- determine an abnormal circulation level using the comparison of the measure of similarity in pulse shape and the concentration level of NO, wherein the abnormal circulation level indicates a blood circulation problem in the tissue.
6 more elements
Dependencies are inferred from the claim text.