Adaptive peritoneal dialysis intra-session adjustments for overall session optimization

A computer implemented method of adjusting intercycle patient parameters during peritoneal dialysis, performed by a system having one or more processors programmed to perform:

• receiving, by the one or more processors of the system, one or more patient parameters during a single peritoneal dialysis session from a sensor;
• receiving, by the one or more processors of the system, one or more dialysis parameters used during the peritoneal dialysis session;
• storing the one or more patient parameters and one or more dialysis parameters in a machine-readable storage medium for storing instructions
• adjusting one or more dialysis parameters for a subsequent cycle of the single peritoneal dialysis session based on the patient parameters and dialysis parameters;
• wherein the step of adjusting one or more dialysis parameters is carried out by at least one of the one or more processors of the system in communication with a peritoneal dialysate generation flow path;
• wherein at least one or more of:
• a) the method further comprises receiving a target fluid removal volume by the one or more processors of the system comparing a volume of effluent removed to the target fluid removal volume by the one or more processors of the system;
• and wherein the step of adjusting one or more dialysis parameters for the subsequent cycle comprises the step of adjusting a dwell time, a number of cycles, or combinations thereof;
• b) the method further comprises the steps of determining a change in patient blood pressure during the peritoneal dialysis cycle by the one or more processors of the system;
• and
• decreasing a dialysate osmotic agent concentration in a subsequent cycle if the change in patient blood pressure exceeds a predetermined threshold;
• c) wherein the one or more patient parameters include a patient goal;
• wherein the patient goal is any one of an expected fluid intake, an expected diet, an expected dialysis schedule, and combinations thereof;
• and wherein the step of adjusting one or more dialysis parameters for the subsequent cycle of the single peritoneal dialysis session comprises increasing the osmotic agent concentration in response to a high expected fluid intake, a high salt diet, an expected dialysis schedule of fewer dialysis sessions, and combinations thereof;
• and/or
• d) the step of adjusting the one or more dialysis parameters for the subsequent cycle comprises increasing (a) the dwell time, (b) the osmotic agent concentration, or (c) combinations thereof, if a patient posture is determined to be erect.