Method for preventing postoperative adhesion of an organ in a wound site
AssigneeNipro Corporation
InventorsYusuke Nakamura, Kazuhisa Matsuda
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Abstract
Provided is a method for preventing postoperative adhesion of an organ in a wound site using the application of an antiadhesive material thereto. The antiadhesive material contains a poly-γ-glutamic acid having a weight-average molecular weight of 600,000 to 13,000,000, or a kinematic viscosity at 37° C. of 2 cSt to 15 cSt when dissolved in distilled water at a concentration of 0.05% by mass and/or a salt thereof, as an effective ingredient. The antiadhesive material may be in a form such as powder, and therefore, for example, is easy to handle even in relatively localized surgery such as endoscopic surgery and can more reliably prevent adhesion.
Claims3
A method for preventing postoperative adhesion of an organ in a wound site comprising:
- applying powder form of a sodium poly-γ-glutamate as a sole component to the wound site of a subject as it is,
- wherein the sodium poly-γ-glutamate is substantially uncrosslinked and is processed into powder form, and
- wherein applying the powder form of the sodium poly-γ-glutamate comprises spraying the powdered sodium poly-γ-glutamate onto the wound site or to surrounding tissue.
Dependencies are inferred from the claim text.