Immunogenic RSV polypeptides
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsSurender Khurana, Hana Golding
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Abstract
This invention provides immunogenic compositions comprising an immune stimulant and an respiratory syncytial virus (RSV) oligopeptide or an unglycosylated RSV polypeptide. The RSV oligopeptides are shown in SEQ ID NO: 3-33. The unglycosylated RSV polypeptide may consist essentially of the ectodomain of an RSV G protein, such as that shown in SEQ ID NO: 2 or the ectodomain of an RSV F protein such as the ectodomain of the F protein shown in SEQ ID NO: 39.
Claims7
An immunogenic composition comprising an immune stimulant and an RSV oligopeptide comprising an amino acid sequence set forth as SEQ ID NO:
- 29, wherein the RSV oligopeptide is less than 50 amino acids in length, and wherein the immune stimulant is in an amount effective to stimulate an immune response to the RSV oligopeptide.
Dependencies are inferred from the claim text.