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US 10,744,114 B2Granted
Use of eupatilin as pharmaceutical composition for prevention and treatment of fibrosis using EMT inhibitory activity
AssigneeOsteoneurogen Inc.
InventorsByung Soo Youn, Han Soo Kim, Ho Sup Yoon
Life of this patent
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Abstract
A pharmaceutical composition contains the chromone derivative of Chemical Formula 1 and a pharmaceutically acceptable salt as an active ingredient, thus effectively inhibiting the activation of EMT to thereby enable the effective suppression of a disease caused by fibrosis of an organ or tissue in vivo due to the activation of EMT.
Claims1
A method of treating a disease caused by fibrosis of an organ or tissue in vivo in a subject in need thereof, comprising:
- providing a pharmaceutical composition comprising 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-chromone or a pharmaceutically acceptable salt thereof, as an active ingredient;
- and
- administering the pharmaceutical composition to the subject, wherein the disease is treated,
- wherein the disease is selected from the group consisting of idiopathic pulmonary fibrosis, myelofibrosis, and kidney fibrosis.
1 more element
Dependencies are inferred from the claim text.