Pharmaceutical dosage form for application to mucous membranes
AssigneeUniversitat Greifswald
InventorsMalte Bogdahn, Kirsten Kirsch, Michael Grimm, Mirko Koziolek, Werner Weitschies
Life of this patent
Estimating the term…
Abstract
The present invention relates to a pharmaceutical dosage form for application to a mucous membrane, in particular to a buccal, intestinal, rectal or vaginal mucous membrane, comprising at least one sheet like, in particular film shaped, foil shaped or wafer shaped preparation comprising the active pharmaceutical ingredient, a release mechanism, and a trigger mechanism, wherein the trigger mechanism is adapted to trigger, at a predetermined site of action, in particular of the gastrointestinal tract, of the rectum or of the vagina, the release of the sheet like preparation by the release mechanism.
Claims13
A pharmaceutical dosage form for the application to an esophageal mucous membrane, comprising
- a film shaped, foil shaped, wafer shaped or strip shaped preparation comprising an active pharmaceutical ingredient,
- a release mechanism;
- and
- a trigger mechanism, wherein
- the trigger mechanism is adapted to trigger, at a predetermined site of action, the release of the preparation by the release mechanism, and wherein the release mechanism is adapted to release said preparation while moving along the esophageal mucous membrane, wherein the pharmaceutical dosage form further comprises a shell, wherein the shell contains the preparation, and wherein the shell comprises an aperture as part of the release mechanism configured to allow said preparation to leave the shell, and wherein the trigger mechanism is a holding device that is a part of or is attached to the preparation, and wherein the trigger mechanism is adapted to be fixed in an oral cavity, or wherein the trigger mechanism is adapted to be held in a hand during administration of the pharmaceutical dosage form, such that the preparation is unrolled or unfolded while the dosage form moves down the esophageal mucous membrane and leaves the shell through the aperture.
Dependencies are inferred from the claim text.