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US 10,744,077 B2Granted
Oral care compositions and methods of use
AssigneeColgate-Palmolive Company
InventorsLisa Manus, Julia Dreifus
Life of this patent
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Abstract
This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.
Claims21
An oral care buffering composition comprising:
- a. a basic amino acid in free or salt form wherein the amino acid is arginine, and wherein the arginine is present from 0.1%-0.6% by wt. of the total composition:
- b. zinc oxide, wherein the zinc oxide is present in an amount from 0.75%-1.25% by wt. of the total composition, and zinc citrate, wherein the zinc oxide citrate is present in an amount from 0.25%-0.75% by wt. of the total composition:
- and
- c. an orally acceptable carrier,
- wherein the oral care composition provides a buffering effect against acidic conditions in the oral cavity following acid challenge or sucrose challenge, wherein the buffering effect is greater than a corresponding buffering effect of compositions comprising arginine, zinc oxide or zinc citrate alone;
- wherein the composition is configured to be maintained at a pH over 7.0 when challenged in an acidic aqueous solution with 0.01M aqueous HCl in an amount of about 60% v/v based on the total volume of the solution.
3 more elements
Dependencies are inferred from the claim text.