Disruptive dressing for use with negative pressure and fluid instillation

A system for softening materials at a tissue site, comprising:

• a contact layer formed from a compressible material and configured to be positioned adjacent the tissue site, the contact layer comprising walls defining a plurality of through-holes;
• a cover adapted to form a sealed space over the contact layer and the tissue site for receiving a negative pressure from a negative-pressure source;
• and
• wherein the contact layer has a first thickness at ambient pressure, wherein the contact layer is configured to compress to a second thickness in response to the negative pressure, wherein the second thickness is less than the first thickness, wherein the through-holes are configured to receive tissue in the through-holes in response to negative pressure in the sealed space to form nodules in the tissue site, wherein the nodules have a height no greater than the second thickness.