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US 10,743,896 B2Granted
Ocular ultrasound probe
AssigneeDoheny Eye Institute
InventorMark S. Humayun
Life of this patent
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Abstract
Devices, systems and methods for ocular ultrasound are provided having therapeutic and/or diagnostic applications. In one aspect, an ocular probe is disclosed that is uniquely configured for use in the eye on the basis of shape and frequency. The ocular probe may be multi-functional, providing sensor, optical or other functionality in additional to ultrasound energy.
Claims15
A method for treating a disease or disorder of an ocular blood flow, the method comprising:
- a) supplying microbubbles to a blockage within a retinal vessel, said supplying including supplying the microbubbles to an occluded retinal vein,
- b) using an ocular ultrasound probe, which includes a housing and an ultrasound transducer element in the housing,
- wherein an outer surface of said housing has a shape of a semicircle, a crescent, or a wedge and is dimensioned to be placed in contact with and onto an eye or an eyelid at a first location corresponding to a second location, the second location being a location designated for placement of a contact lens on the eye,
- to position said probe at said first location such that the outer surface is in contact with a surface of the eye or the eyelid;
- and
- to retain and secure the probe at the eyelid with a use of an outer ring of the housing to hold the probe in place,
- and
- c) reducing or eliminating the blockage by applying ultrasound energy having a frequency in a range between 1 MHz and 10 MHz from the so-secured probe to a retinal site in the eye to initiate cavitation at the microbubbles while avoiding delivery of said energy to a crystalline lens of the eye and simultaneously optically viewing the retinal site with an optical viewing instrument through an opening in the ultrasound transducer.
5 more elements
Dependencies are inferred from the claim text.