Stapler for forming multiple tissue plications

A stapling device comprising:

• a cartridge comprising at least three groups of slots, wherein each group comprises at least two slots, and each slot contains a staple;
• a cartridge support coupled to the cartridge;
• an anvil facing the cartridge;
• a staple driver configured to engage and eject the staples in each group of slots sequentially when the staple driver is repeatedly moved from a retracted position to an extended position;
• and
• an indexing mechanism configured to rotate the cartridge relative to the cartridge support, such that the staple driver engages and ejects staples in a first group of slots before engaging and ejecting the staples in a second group of slots.

A stapling device comprising:

• a cartridge comprising a plurality of slots that includes at least a first group of slots offset from a second group of slots;
• an anvil facing the cartridge and including a plurality of recessed areas;
• a staple driver configured to engage and eject staples from the plurality of slots of the cartridge when the staple driver is moved from a first position to a second position;
• and
• an indexing mechanism configured to move one of the cartridge or the staple driver incrementally relative to the other of the cartridge or the staple driver, such that the staple driver engages and ejects staples disposed in the second group of slots after engaging and ejecting the staples in the first group of slots, such that the stapling device is configured to eject successive groups of staples without reloading the cartridge;
• wherein the indexing mechanism comprises a spring configured to move one of the cartridge or the staple driver relative to a fixed position of the other of the cartridge or the staple driver.