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US 10,743,798 B2Granted
Method and apparatus for automated detection of suppression of TEOAE by contralateral acoustic stimulation
AssigneePATH medical GmbH
InventorsAndre Lodwig, Johann Oswald, Thomas Janssen
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Abstract
The invention is directed to a method of generating and measuring transiently evoked otoacoustic emissions (TEOAE) acoustic signals generated in the cochlea using a scheme of stimulating both inner ears simultaneously, left ear alone, and right ears alone with at least two different first and second averaging buffers per ear in a switching scheme with automated detection of contralateral suppression of TEOAE via statistical analysis of the differences of suppressed and unsuppressed responses.
Claims17
A method to automatically detect Transient-evoked Otoacoustic emissions (TEOAE) contralateral suppression, comprising:
- a. exposing a patient to periodic sequences of sound stimuli to generate TEOAE stimuli phase locked waveforms given off by left and right inner ears by periodically switching so as to provide first stimuli to both inner ears, a second stimulus to the left inner ear alone, and a third stimulus to the right inner ear alone;
- b. sequentially recording the TEOAE stimuli phase locked waveforms given off by the left and right inner ears, the left inner ear alone, and the right inner ear alone, wherein:
- i. a left unsuppressed buffer receives and averages all TEOAE stimuli phase locked waveforms that are recorded in the left inner ear at times when the second stimulus is provided to the left inner ear and no stimulus is provided to the right inner ear so as to result in an averaged left unsuppressed TEOAE waveform,
- ii. a left suppressed buffer receives and averages all TEOAE stimuli phase locked waveforms that are recorded in the left inner ear at times when the first stimuli are provided to the left and right inner ears so as to result in an averaged left suppressed TEOAE waveform,
- iii. a right unsuppressed buffer receives and averages all TEOAE stimuli phase locked waveforms that are recorded in the right inner ear at times when the third stimulus is provided to the right inner ear and no stimulus is provided to the left inner ear so as to result in an averaged right unsuppressed TEOAE waveform, and
- iv. a right suppressed buffer receives and averages all TEOAE stimuli phase locked waveforms that are recorded in the right inner ear at times when the first stimuli are provided to the left and right inner ears so as to result in an averaged right suppressed TEOAE waveform;
- c. calculating:
- i. a difference averaged TEOAE waveform for the left inner ear by subtracting the averaged left suppressed TEOAE waveform from the averaged left unsuppressed TEOAE waveform and
- ii. a difference averaged TEOAE waveform for the right inner ear by subtracting the averaged right suppressed TEOAE waveform from the averaged right unsuppressed TEOAE waveform;
- and
- d. applying morphological analysis to an overall shape of the difference averaged TEOAE waveform for each inner ear to detect if the TEOAE contralateral suppression is present or absent in the right inner ear, the left inner ear, or both right and left inner ears.
8 more elements
An apparatus to automatically detect Transient-evoked Otoacoustic emissions (TEOAE) contralateral suppression comprising:
- a. a sound generator configured to expose a patient to periodic sequences of sound stimuli to evoke TEOAE stimuli phase locked waveforms given off by left and right inner ears by periodically switching so as to provide first stimuli to both inner ears, a second stimulus to the left inner ear alone, and a third stimulus to the right inner ear alone;
- b. a recorder configured to sequentially record the TEOAE stimuli phase locked waveforms given off by the left and right inner ears, the left inner ear alone, and the right inner ear alone;
- c. a left unsuppressed buffer configured to receive and average all TEOAE stimuli phase locked waveforms that are recorded in the left inner ear at times when the second stimulus is provided to the left inner ear and no stimulus is provided to the right inner ear so as to result in an averaged left unsuppressed TEOAE waveform;
- d. a left suppressed buffer configured to receive and average all TEOAE stimuli phase locked waveforms that are recorded in the left inner ear at times when the first stimuli is provided to the left and right inner ears so as to result in an averaged left suppressed TEOAE waveform;
- e. a right unsuppressed buffer configured to receive and average all TEOAE stimuli phase locked waveforms that are recorded in the right inner ear at times when the third stimulus is provided to the right inner ear and no stimulus is provided to the left inner ear so as to result in an averaged right unsuppressed TEOAE waveform;
- and
- f. a right suppressed buffer configured to receive and average all TEOAE stimuli phase locked waveforms that are recorded in the right inner ear at times when the first stimuli is provided to the left and right inner ears so as to result in an averaged right suppressed TEOAE waveform;
- and
- g. a computer configured to:
- i. calculate a difference averaged TEOAE waveform for the left inner ear by subtracting the averaged left suppressed TEOAE waveform from the averaged left unsuppressed TEOAE waveform,
- ii. calculate a difference averaged TEOAE waveform for the right inner ear by subtracting the averaged right suppressed TEOAE waveform from the averaged right unsuppressed TEOAE waveform, and
- iii. apply a morphological analysis to an overall shape of the difference averaged TEOAE waveform for each inner ear to detect if the TEOAE contralateral suppression is present or absent in the right inner ear, the left inner ear, or both right and left inner ears.
9 more elements
Dependencies are inferred from the claim text.