Back to results
US 10,731,131 B2Granted
Dendritic cell generator
AssigneeNortheastern University
InventorsShashi K. Murthy, Bradley B. Collier
Life of this patent
Estimating the term…
Abstract
Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.
Claims10
A cell culture system comprising:
- (i) one or more fluid reservoirs;
- (ii) a pump operably coupled to the one or more fluid reservoirs;
- (iii) a cell culture chamber fluidically coupled to the one or more fluid reservoirs, wherein the cell culture chamber comprises a fluidic channel having an inlet, an outlet, and a cell binding surface;
- and
- (iv) a mounting area comprising a base, the mounting area supporting the cell culture chamber such that the fluidic channel is positioned at an acute angle with respect to the base in a manner that the inlet is below the outlet.
2 more elements
Dependencies are inferred from the claim text.