Saliva glucose measurement devices and methods
AssigneeArizona Board of Regents on behalf of Arizona State University
InventorsJeffrey LaBelle, Chi Lin, Jonus Reyna, Amnah Alkhan, Cael Muggeridge, Susan Sheffield
Life of this patent
Estimating the term…
Abstract
Devices and methods capable of detecting glucose in saliva (FIG. 12). The devices feature a sensor having a substrate containing electrodes and one or more reagents on the electrodes. A detection device is operably coupled with the sensor to detect glucose based on measurement of an electrical parameter when electricity is applied to the electrode.
Claims6
A method of detecting a blood glucose level using saliva, the method comprising:
- contacting a sensor containing electrodes and one or more glucose-detection reagents on said electrodes with saliva;
- and
- energizing said electrodes such that a measurement of an electrical parameter indicative of an amount of glucose in said saliva is produced and measured,
- wherein said one or more glucose-detection reagents comprise glucose dehydrogenase (GDH) and ferricyanide in 1X phosphate buffered saline (PBS) buffer.
A method of detecting a blood glucose level using saliva, the method comprising:
- contacting a sensor containing electrodes and one or more glucose-detection reagents on said electrodes with saliva;
- and
- energizing said electrodes such that a measurement of an electrical parameter indicative of an amount of glucose in said saliva is produced and measured, wherein said one or more reagents comprise glucose dehydrogenase flavine-adenine dinucleotide (GDH-FAD) and ferricyanide in 1×PBS buffer.
A method of monitoring a glucose level against a desired range in a patient, comprising:
- contacting a sensor containing electrodes and one or more glucose-detection reagents on said electrodes with saliva;
- and
- energizing said electrodes such that a measurement of an electrical parameter indicative of an amount of glucose in said saliva is produced and measured against said desired range,
- wherein said one or more glucose-detection reagents comprise glucose dehydrogenase (GDH) and ferricyanide in 1×PBS buffer.
A method of monitoring a glucose level against a desired range in a patient, comprising:
- contacting a sensor containing electrodes and one or more glucose-detection reagents on said electrodes with saliva;
- and
- energizing said electrodes such that a measurement of an electrical parameter indicative of an amount of glucose in said saliva is produced and measured against said desired range, wherein said one or more reagents comprise glucose dehydrogenase flavine-adenine dinucleotide (GDH-FAD) and ferricyanide in 1×PBS buffer.
Dependencies are inferred from the claim text.