Method of producing deuterated haloform
AssigneeDeuteroChem Sdn Bhd
InventorsNatha Dean Tansukawat, Alyaa Ezzati Binti Muhammad Hakim See
Life of this patent
Estimating the term…
Abstract
The invention relates to methods of producing deuterated haloform, and apparatus for such methods. In an aspect of the invention, there is provided a method to produce deuterated haloform, the method comprising: (a) providing a mixture comprising a compound of formula (I) heavy water, and a catalyst of formula (II), wherein each X in formula (I) is independently a halogen, and R1 is an aliphatic group, or an aryl group, wherein at least one of R2, R3, R4, R5, and R6 is an anionic functional group, a polymer, or a linker attached to a polymer; (b) heating the mixture to displace the trihalocarbon anion; and (c) forming the deuterated haloform.
Claims18
A method to produce deuterated haloform, the method comprising:
- (a) providing a mixture comprising a compound of formula (I)
- heavy water, and a catalyst of formula (II),
- wherein each X in formula (I) is independently a halogen, and R1 is an aliphatic group or an aryl group,
- wherein at least one of R2, R3, R4, R5, and R6 is a polymer, or a linker attached to the polymer;
- (b) heating the mixture to displace the trihalocarbon anion;
- (c) forming the deuterated haloform;
- and
- (d) purifying the deuterated haloform, wherein purifying the deuterated haloform comprises distilling the deuterated haloform to form a distillate, and passing the distillate through a sieve with a mesh diameter equal to or less than a particle size of the polymer.
Dependencies are inferred from the claim text.