Near-IR glucose sensors

A compound of Formula I:

• or a tautomer or a salt thereof,
• wherein the dotted lines denote a bond or absence of a bond;
• when the dotted line connecting R1 and O is a bond, R1 is CX1X2 and R15 is absent;
• and
• when the dotted line connecting R1 and 0 is absence of a bond, R15, at each occurrence, is independently H or C1-C6 alkyl, and R1, at each occurrence, is H, optionally substituted C1-C6 alkyl, optionally substituted C2-C6 alkenyl, optionally substituted C2-C6 alkynyl, optionally substituted C2-C10 heteroalkyl, polymerizable moiety, an NIR dye moiety, an electron-withdrawing group, or an electron-donating group;
• X1 and X2 are independently H or C1-C6 alkyl;
• R2 is H or C1-C6 alkyl;
• Z is a C6-C14 arylene optionally substituted with R11, R12, R14, and L2R13;
• R3, R4, R5, R6, R7, R8, R11, R12, R13 and R14 are independently H, optionally substituted C1-C6 alkyl, optionally substituted C2-C6 alkenyl, optionally substituted C2-C6 alkynyl, optionally substituted C2-C10 heteroalkyl, polymerizable moiety, NIR dye moiety, electron-withdrawing group, or electron-donating group;
• R9 and R10 are independently H, C1-C6 alkyl, polymerizable moiety, or NIR dye moiety;
• L1, L2, and L3 are independently a bond or a linker group;
• and
• wherein at least one R1, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, or R14 is an NIR dye moiety and at least one R1, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, or R14 is a polymerizable moiety.