Encapsulated cannabinoid formulations for transdermal delivery
AssigneeNutrae, LLC
InventorsChristopher G. Witowski, Jacqueline L. Salm
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Abstract
Preparation of cannabinoid formulations containing: Δ9-tetrahydrocannabinol (Δ9-THC), Δ8-tetrahydrocannabinol (Δ8-THC), Δ9-tetrahydrocannabinolic acid (THCa), cannabidiol (CBD), cannabidiolic acid (CBDa), cannabigerol (CBG), cannabichromene (CBC) and cannabinol (CBN), either alone or in combinations henceforth known as cannabis, have been created using an emulsification process to encapsulate cannabinoids. The aqueous-based method involves micellular encapsulation of cannabinoids, a method that has been used to increase the bioavailability of poorly permeable, lipophilic drugs. The present invention demonstrates the viability of transdermal delivery with gels and patches for consistent and sustained cannabinoid dosing.
Claims14
A cannabinoid composition capable of trans canal delivery, comprising:
- a cannabinoid composition further comprising:
- a cannabinoid preparation ranging from 0.1% to 20% (w/w);
- at least one surfactant ranging from 5% to 50% (w/w);
- at least one co-solvent ranging from 10% to 70% (w/w);
- water ranging from 16% to 60% (w/w);
- and
- wherein the cannabinoid composition is capable of topical application and wherein the cannabinoid preparation is encapsulated by surfactants to form micelles having uni-, bi-, or multi-lamellar structures.
Dependencies are inferred from the claim text.