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US 10,708,263 B2Granted
Salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
AssigneeGalapagos NV
InventorsPiet Wigerinck, Nicolas Luc Sabourault
Life of this patent
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Abstract
The present invention discloses salts of a Compound 1: useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
Claims6
A pharmaceutically acceptable salt of a compound according to Formula (I):
- wherein the salt is a 1:1 free base/maleic acid salt in a crystalline form characterized at least by an X-ray powder diffraction peak at each of the following positions:
- 4.3, 8.3, 12.0, 15.0, 16.3, 18.1, 18.7, 19.3, 20.0, 20.4, 22.6, 23.5, 23.9, 24.0, 24.5, 25.4, 25.8, and 28.7±0.2° 2θ.
Dependencies are inferred from the claim text.