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US 10,706,539 B2Granted
Subtraction algorithm for detection of tumors
AssigneeRaytheon Company
InventorsRaymond Samaniego, Lauren G. Hatchell, Tuan T Tran, John L. Tomich, Bryan D. Anderson
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Abstract
A system and method for detecting tumors. Three-dimensional scans of a patient are performed with penetrating radiation, before and/or after the injection of a contrast agent. Raw density arrays are formed from the scans. The median density within an organ is calculated and subtracted from each of the raw density arrays, to form offset arrays. The offset arrays are subtracted pairwise and the differences are summed to form a discriminator array.
Claims20
A method for detecting a tumor, the method comprising:
- determining, in each of a plurality of raw density arrays, a respective median value within a region of the respective raw density array, each of the plurality of raw density arrays being a three dimensional array having a plurality of array elements, each of the raw density arrays being associated with a respective point in time, each element of each of the raw density arrays representing a density of a portion of a patient at the respective point in time;
- forming a plurality of offset density arrays, each corresponding to a respective one of the raw density arrays, the forming of the offset density arrays comprising subtracting, from each of the raw density arrays, the respective median value;
- forming a first difference array, the forming of the first difference array comprising subtracting, from a first offset density array, a second offset density array, the second offset density array being associated with a later point in time than the first offset density array;
- forming a second difference array, the forming of the second difference array comprising subtracting, from a third offset density array, a fourth offset density array, the fourth offset density array being associated with a later point in time than the third offset density array;
- and
- forming a discriminator array, the forming of the discriminator array comprising adding the first difference array and the second difference array.
3 more elements
A system for detecting a tumor, the system comprising:
- a scanner for scanning the object with penetrating radiation and measuring the transmission of the penetrating radiation through a patient;
- a processing circuit;
- and
- a display,
- the processing circuit being configured to:
- determine, in each of a plurality of raw density arrays, a respective median value within a region of the respective raw density array, each of the plurality of raw density arrays being a three dimensional array having a plurality of array elements, each of the density arrays being associated with a point in time, each element of each of the raw density arrays representing a density of a portion of a patient at the respective point in time;
- form a plurality of offset density arrays, each corresponding to a respective one of the raw density arrays, the forming of the offset density arrays comprising subtracting, from each of the raw density arrays, the respective median value;
- form a first difference array, the forming of the first difference array comprising subtracting, from a first offset density array, a second offset density array, the second offset density array being associated with a later point in time than the first offset density array;
- form a second difference array, the forming of the second difference array comprising subtracting, from a third offset density array, a fourth offset density array, the fourth offset density array being associated with a later point in time than the third offset density array;
- and
- form a discriminator array, the forming of the discriminator array comprising adding the first difference array and the second difference array.
8 more elements
Dependencies are inferred from the claim text.