System and method for low rank approximation of high resolution MRF through dictionary fitting
AssigneeCase Western Reserve University
InventorsMark A. Griswold, Mingrui Yang, Debra McGivney
Life of this patent
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Abstract
A system and method is provided for generating a map of a tissue property in a subject using magnetic resonance fingerprinting (MRF) and a compressed MRF dictionary, where the compressed MRF dictionary has a significantly reduced memory requirement relative to a standard MRF dictionary. The method includes performing a randomized singular value decomposition (rSVD) on a MRF dictionary to produce the compressed MRF dictionary. MRF data is then acquired and compared to the MRF dictionary to identify the tissue property from the region of interest in the subject. A tissue property map is then generated based on the tissue in the region of interest of the subject.
Claims25
A method for generating a map of a tissue property in a subject using magnetic resonance fingerprinting (MRF) and a compressed MRF dictionary, the compressed MRF dictionary having a reduced memory requirement relative to a MRF dictionary (D), the method comprising:
- accessing a compressed MRF dictionary with a MRF system, the compressed MRF dictionary generated by performing a randomized singular value decomposition (rSVD) on a MRF dictionary (D), the compressed MRF dictionary comprising a series of singular vectors and a series of singular values from the MRF dictionary (D);
- acquiring MRF data from the tissue in the region of interest, and comparing the MRF data to the compressed MRF dictionary to identify the tissue property from the region of interest;
- and
- generating the map of the tissue property based on the tissue in the region of interest of the subject.
A method for generating a map of a tissue property in a subject using magnetic resonance fingerprinting (MRF), the method comprising:
- acquiring MRF data from a region of interest in a subject by performing a pulse sequence using a series of varied sequence blocks to elicit a series of signal evolutions;
- applying curve fitting to at least a portion of a MRF dictionary to generate a fitted MRF dictionary;
- and
- comparing the MRF data to the fitted MRF dictionary to generate a tissue property map from the region of interest.
A magnetic resonance fingerprinting (MRF) system comprising:
- a magnet system configured to generate a polarizing magnetic field about at least a portion of a subject;
- a magnetic gradient system including a plurality of magnetic gradient coils configured to apply at least one magnetic gradient field to the polarizing magnetic field;
- a radio frequency (RF) system configured to apply an RF field to the subject and to receive magnetic resonance signals from the subject using a coil array;
- a computer system programmed to:
- access a compressed MRF dictionary with the MRF system, the compressed MRF dictionary generated by performing a randomized singular value decomposition (rSVD) on a MRF dictionary (D), the compressed MRF dictionary comprising a series of singular vectors and a series of singular values from the MRF dictionary (D);
- acquire MRF data from the tissue in the region of interest, and comparing the MRF data to the compressed MRF dictionary to identify the tissue property from the region of interest;
- and
- generate the map of the tissue property based on the tissue in the region of interest of the subject.
Dependencies are inferred from the claim text.