Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof

A device for detecting an analyte comprising:

• a housing comprising a first housing member and a second housing member, wherein the housing further comprises:
• an inlet;
• a first force member in contact with a first force actuator outlet;
• a second force member in contact with a second force actuator outlet;
• a movable locking member contacting the first force member and the second force member;
• a first and second analyte detection membrane system comprising in the following order:
• a conjugate pad;
• an optional permeable membrane;
• a test membrane;
• an absorbent member;
• and
• a first flexible or fixed attachment member attached to the movable locking member and the conjugate pad of the first analyte detection membrane system;
• a second flexible or fixed attachment member attached to the movable locking member and the conjugate pad of the second analyte detection membrane system;
• and
• a channel system or membrane that transports fluid from the inlet to the first and second analyte detection membrane systems;
• wherein at least a portion of each of the conjugate pad, permeable membrane, test membrane, and absorbent member are substantially parallel to each other;
• wherein the first and second analyte detection systems are capable of being compressed;
• wherein the first force member contacts the absorbent member of the first analyte detection membrane system and when the first force member is engaged applies pressure substantially perpendicular to the first analyte detection membrane system;
• and
• wherein the second force member contacts the absorbent member of the second analyte detection membrane system and when the second force member is engaged applies pressure substantially perpendicular to the second analyte detection membrane system.