Recombinant yeast producing 3-hydroxypropionic acid and method for producing 3-hydroxypropionic acid using the same

A recombinant yeast selected from Saccharomyces cerevisiae, Kazachstania exigua, Kazachstania bulderi, and Candida humilis and comprising an active 3-hydroxypropionic acid (3-HP) biosynthetic pathway of [Pyruvate→Acetaldehyde→Acetyl-CoA→Malonyl-CoA→Malonate semialdehyde→3-HP], wherein the yeast comprises:

• an exogenous gene encoding acetylating acetaldehyde dehydrogenase (AADH), which converts acetaldehyde directly to acetyl-CoA and that has an amino acid sequence of at least 95% sequence identity to SEQ ID NO:
• 164;
• an endogenous or exogenous gene encoding an acetyl-CoA carboxylase (ACC) that has an amino acid sequence of at least 95% sequence identity to SEQ ID NO:
• 101;
• an exogenous gene encoding a malonyl-CoA reductase (MCR) that has an amino acid sequence of at least 95% sequence identity to SEQ ID NO:
• 203;
• and
• an exogenous gene encoding an hydroxypropionate dehydrogenase (HPDH) that has an amino acid sequence of at least 95% sequence identity to SEQ ID NO:
• 236.