Device for propagating microtissues
AssigneeInsphero AG
InventorsJan Lichtenberg, Wolfgang Moritz, Jens Kelm
Life of this patent
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Abstract
Disclosed are devices for propagating at least one microtissue, methods for manufacturing such devices, and the use us such devices, said devices comprise at least one well, wherein said at least one well comprises an open upper section comprising an open upper end and an open lower end, and a lower section comprising an open upper end and a bottom end, wherein the upper section and the lower section are in fluid communication, and wherein the bottom end of the lower section of at least one well of said plurality of wells is provided with a well bottom, said lower section of said at least one well has a smaller cross-sectional area than the open upper section of the same well.
Claims17
A multiwell plate comprising a plurality of wells for propagating at least one microtissue, wherein each of said plurality of wells comprises an upper section with an upper opening of the well, a lower section with a closed well bottom, and a single narrowing from the upper opening to the closed well bottom, the narrowing being comprised in an intermediate section arranged between the upper section and the lower section,
- wherein the upper section and the lower section are in fluid communication, and wherein the lower section of each well has a smaller cross-sectional area than the upper section of the same well,
- wherein the lower section is eccentrically arranged with respect to the longitudinal axis of the upper section of each well,
- wherein the intermediate section further comprises a pipetting stage and a chute, the pipetting stage and the chute being comprised in the single narrowing of the well, wherein said pipetting stage has an inclination and said chute being provided between the pipetting stage and the lower section,
- and wherein the chute has a gradually increasing inclination, the inclination being larger than the slope of the pipetting stage.
Dependencies are inferred from the claim text.