Crystalline forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino} acetic acid and processes for preparation thereof
AssigneeCrystal Pharmaceutical (Suzhou) Co., Ltd.
InventorsMinhua Chen, Yanfeng Zhang, Po Zou, Jinqiu Wang, Xiaoyu Zhang
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Abstract
The present disclosure relates to novel crystalline forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino} acetic acid and processes for preparation and uses thereof. Crystalline form CS1, form CS2 and form CS8 of the present disclosure can be used for preparing drugs treating anemia, which providing new choices for preparing drugs of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino} acetic acid, and having very important value for drug development.
Claims20
A crystalline form CS1 of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino} acetic acid, wherein the X-ray powder diffraction pattern shows characteristic peaks at 2theta values of 13.9°±0.2°, 15.3°±0.2°, 15.6°±0.2° and 26.8°±0.2° using CuKα radiation.
A crystalline form CS2 of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino} acetic acid, wherein the X-ray powder diffraction pattern shows characteristic peaks at 2theta values of 14.1°±0.2°, 15.0°±0.2° and 18.3°±0.2° using CuKα radiation.
A crystalline form CS8 of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino} acetic acid, wherein the X-ray powder diffraction pattern shows characteristic peaks at 2theta values of 21.2°±0.2°, 22.6°±0.2° and 26.8°±0.2° using CuKα radiation.
Dependencies are inferred from the claim text.