Porcine epidemic diarrhea virus vaccine
OwnerLuis Alejandro Hernandez, Arun V. Iyer +5inventors
InventorsLuis Alejandro Hernandez, Arun V. Iyer, Dianna M. Murphy Jordan, Abby Rae Patterson, Michael B. Roof, Eric Martin Vaughn, Joseph Gilbert Victoria
Life of this patent
Estimating the term…
Abstract
The present invention relates to immunogenic compositions, wherein the immunogenic compositions include a recombinant spike antigen porcine epidemic diarrhea virus (PEDV). The immunogenic compositions commonly include an oil-in-water emulsion as an adjuvant. Methods for producing the immunogenic compositions and the recombinant PEDV spike antigen are also provided.
Claims16
An immunogenic composition comprising a recombinant spike antigen of porcine epidemic diarrhea virus (PEDV) having a heterologous C-terminal domain and a heterologous transmembrane domain, and an oil-in-water emulsion as an adjuvant, wherein the porcine epidemic diarrhea virus (PEDV) is a PEDV of North American origin and
- a. wherein the spike antigen is encoded by a nucleic acid sequence that is at least 95% identical with SEQ ID NO:
- 8 over the length of SEQ ID NO:
- 8.
Dependencies are inferred from the claim text.