Methods and compositions for treating cancer
AssigneesJanssen Oncology, Inc., British Technology Group Limited
InventorsAlan H. Auerbach, Arie S. Belldegrun, Johann de Bono
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Abstract
Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17α-hydroxylase/C17, 20-lyase inhibitor, such as abiraterone acetate (i.e., 3β-acetoxy-17-(3-pyridyl) androsta-5, 16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17α-hydroxylase/C17, 20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
Claims9
A method for the treatment of a refractory prostate cancer in a human comprising administering to said human a therapeutically effective amount of at least two anti-cancer agents, wherein the at least two anti-cancer agents are:
- (a) abiraterone acetate or a pharmaceutically acceptable salt thereof, and
- (b) a prednisolone.
Dependencies are inferred from the claim text.