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US 10,702,537 B2Granted
Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of methamphetamine use and of HIV infection
AssigneeBoard of Supervisors of Louisiana State University and Agricultural and Mechanical College
InventorsNicholas E. Goeders, Christopher Dalton Schmoutz
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Abstract
A method of treating a condition of in a human patient comprising pharmacologically activating a translocator protein of 18 kDa (TSPO), wherein the condition is one of a chronic methamphetamine addiction, a medical consequence of methamphetamine use; a behavioral consequence of methamphetamine use, an HIV associated cognitive motor disorder, an HIV-associated neurodegenerative disorder, and a neuroinflammatory response.
Claims12
A method of treating a condition in a human patient comprising:
- pharmacologically activating a translocator protein of 18 kDa (TSPO) by administering a therapeutically effective amount of a pharmaceutical composition to the patient;
- wherein the pharmaceutical composition includes one or more peripheral benzodiazepine receptor ligands, or one or more therapeutically acceptable salts, clathrates, stereoisomers, or enantiomers, of these compounds or mixtures thereof, which activate the TSPO;
- wherein the condition is one of
- a chronic methamphetamine addiction;
- a medical consequence of methamphetamine use;
- and
- a behavioral consequence of methamphetamine use.
4 more elements
Dependencies are inferred from the claim text.