Compositions and methods relating to the radioprotective effects of apilimod
AssigneeAI Therapeutics, Inc.
InventorsSean Landrette, Tian Xu, Jonathan M. Rothberg, Henri Lichenstein
Life of this patent
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Abstract
The present disclosure relates to methods for preventing or treating a radiation-induced disease, disorder, or condition by administering apilimod to a subject in need thereof, and related compositions.
Claims19
A method for preventing radiation-induced injury or acute radiation syndrome (ARS) in a subject in need thereof due to the subject's exposure to or expected exposure to a dose of body penetrating radiation equal to 2 or more gray (Gy), the method comprising parenterally administering an amount apilimod, or a pharmaceutically acceptable salt thereof, to the subject before, during or after the subject's exposure to the dose of radiation, either alone or in combination with one or more additional therapeutic agents.
Dependencies are inferred from the claim text.