Treatment of conditions through pharmacological modulation of the autonomic nervous system
AssigneePalo Alto Investors
InventorsAnthony Joonkyoo Yun, Patrick Yuarn-Bor Lee
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Abstract
Methods are provided for treating a subject for a condition caused by an abnormality in the subject's autonomic nervous system. In accordance with the subject methods, at least a portion of a subject's autonomic nervous system is pharmacologically modulated with at least one beta-blocker in a manner that is effective to treat the subject for the condition. The subject methods find use in the treatment of a variety of different conditions, where such conditions include various disease conditions. Also provided are systems and kits for use in practicing the subject methods.
Claims12
A method of treating a subject for an inflammatory respiratory condition caused by an autonomic nervous system abnormality characterized by a sympathetic bias, the method comprising:
- modulating at least a portion of said subject's autonomic nervous system by administering an effective amount of a beta-blocker to said subject to treat said subject for an inflammatory respiratory condition wherein the inflammatory respiratory condition is acute respiratory distress syndrome and wherein said beta-blocker is chosen from atenolol, betaxolol, bisoprolol, carvedilol, esmolol, labetalol, metoprolol, nadolol, pindolol, propranolol, sotalol, timolol, acebutalol, oxprenolol, carvedilol, and entbutolol.
Dependencies are inferred from the claim text.