AZA-pyridone compounds and uses thereof

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, wherein the compound of Formula (I) has the structure:

• wherein:
• is a single bond or double bond;
• R1 is selected from the group consisting of hydrogen, an unsubstituted C1-4 alkyl, —C(═O)Y1, —C(═O)—O—Y1, —(CH2)—O—C(═O)—Y1, (CH2)—O—C(═O)—O—Y1, (CHCH3)—O—C(═O)—Y1 and —(CHCH3)—O—C(═O)—O—Y1;
• R2 is selected from the group consisting of hydrogen, an optionally substituted C1-6 alkyl, an optionally substituted heterocyclyl, an optionally substituted cycloalkyl(C1-6 alkyl), an optionally substituted aryl(C1-6 alkyl), an optionally substituted heteroaryl(C1-6 alkyl) and an optionally substituted heterocyclyl(C1-6 alkyl);
• R3a and R3b are independently hydrogen or an optionally substituted C1-4 alkyl;
• R4 and R5 are taken together with the carbon to which they are attached to form an optionally substituted tricyclic cycloalkenyl or an optionally substituted tricyclic heterocyclyl comprising one or two heteroatoms selected from the group consisting of N, O, and S;
• R6 is selected from the group consisting of hydrogen, halogen, —CN, an optionally substituted C1-6 alkyl, an optionally substituted aryl, an optionally substituted heteroaryl, —CH2OH, —CH(Y2)(OH) and —C(O)Y2;
• Y1 and Y2 are independently selected from the group consisting of an optionally substituted C1-6 alkyl, an optionally substituted C3-6 cycloalkyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted heterocyclyl, a mono-substituted amino, a di-substituted amino and —C(R7)NHR8;
• and
• R7 and R8 are independently hydrogen or an optionally substituted C1-4 alkyl.