Methods and compositions for sleep disorders and other disorders
AssigneeIntra-Cellular Therapies, Inc.
InventorsSharon Mates, Allen Fienberg, Lawrence P. Wennogle
Life of this patent
Estimating the term…
Abstract
Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.
Claims12
A method for the treatment of one or more sleep disorders comprising administering to a patient in need thereof a Compound of Formula I:
- wherein X is O, —NH— or N(CH3);
- and Y is —O— or C(O)—, in free or pharmaceutically acceptable salt form, wherein the amount of said Compound of Formula I administered is from 0.1 mg to 20 mg, in free or pharmaceutically acceptable salt form, provided that in the case of a salt, the weight is calculated as the free base, wherein the patient does not have schizophrenia.
Dependencies are inferred from the claim text.