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US 10,702,466 B2Granted
Emulsions comprising at least one retinoid and benzoyl peroxide
AssigneeGalderma Research & Development
InventorsClaire Mallard, Fabienne Louis, Nathalie Willcox
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Abstract
Stable dermatological/cosmetic emulsions useful, e.g., for the treatment of acne vulgaris, contain, formulated into a physiologically acceptable medium, a homogeneous dispersion of at least one dispersed retinoid, dispersed benzoyl peroxide, at least one fatty phase, at least one hydrophilic phase and at least one emulsifier.
Claims34
A stable dermatological emulsion comprising:
- 2% to 50% by weight of at least one fatty phase;
- 10% to 90% by weight of at least one hydrophilic phase comprising water;
- 1% to 20% by weight of at least one emulsifier selected from the group consisting of (a) glyceryl stearate and PEG-100 stearate, (b) PEG-6 stearate and PEG-32 stearate, (c) polyoxyethylene (21) stearyl ether, (d) ceteareth-20, (e) PEG-20 methyl glucose sesquistearate, and (f) methyl glucose sesquistearate-type emulsifiers;
- 0.01 to 5% by weight of dispersed adapalene as an active principle;
- and
- 0.025% to 10% by weight of dispersed benzoyl peroxide as an active principle;
- wherein the emulsion is a homogeneous dispersion;
- and
- wherein the adapalene and the benzoyl peroxide are the only active principles in the emulsion.
6 more elements
Dependencies are inferred from the claim text.