Method and system for calibrating an imaging system

A system, comprising:

• at least one storage medium including a set of instructions;
• and
• at least one processor configured to communicate with the at least one storage medium, wherein when executing the set of instructions, the at least one processor is directed to:
• acquire, from an imaging device, projection data of a phantom comprising a plurality of markers at a plurality of angles of a source of the imaging device;
• determine, based on the projection data of the phantom and coordinates of the plurality of markers in a first coordinate system, a plurality of projection matrices of the first coordinate system and a transformation matrix between the first coordinate system and a second coordinate system, an angle of the source corresponding to a projection matrix of the first coordinate system, the first coordinate system relating to the phantom, and the second coordinate system relating to the imaging device;
• determine a plurality of projection matrices of the second coordinate system based on the plurality of projection matrices of the first coordinate system and the transformation matrix between the first coordinate system and a second coordinate system, a projection matrix of the second coordinate system corresponding to an angle of the source;
• and
• store the plurality of the determined projection matrices of the second coordinate system as an electronic file.

A method implemented on at least one machine that is associated with an imaging device, each of the at least one machine has at least one processor and storage storing a set of instructions, the method comprising:

• acquiring, by the at least one machine, from an imaging device, projection data of a phantom comprising a plurality of markers,
• determining, by the at least one machine, based on the projection data of the phantom and coordinates of the plurality of markers in a first coordinate system, a plurality of projection matrices of a second coordinate system, the first coordinate system being a coordinate system of the phantom, and the second coordinate system being a coordinate system of the imaging device;
• and
• determining, by the at least one machine, based on the plurality of projection matrices of the second coordinate system, a projection coordinate of a source of the imaging device in a third coordinate system, the third coordinate system being an image coordinate system of the imaging device.