Apparatus and method for electroencephalographic examination
AssigneeCerenion Oy
InventorsJukka Kortelainen, Eero Väyrynen, Tapio Seppänen
Life of this patent
Estimating the term…
Abstract
An apparatus comprises a data processing unit (100) which receives electroencephalographic data based on a measurement of a person (110) exposed to anesthetic drug substance which has one or more estimated or measured non-zero levels of concentration in the body (108) of the person (110) as a function of time; and determines and present activity of slow waves of the electroencephalographic data at the one or more estimated or measured levels of the non-zero concentration of the anesthetic drug substance.
Claims13
An apparatus comprising:
- an administration device configured to cause estimated or measured non-zero amounts of an anesthetic drug substance to be introduced into a body of a person and to adjust input of the anesthetic drug substance into the body;
- and
- at least one processor and associated memory configured to:
- receive electroencephalographic data for a brain based on at least one measurement of the person exposed to the estimated or measured non-zero amounts of the anesthetic drug substance, the electroencephalographic data comprising slow waves having a frequency at or below 1 Hz;
- control the administration device to introduce continuously into the body the anesthetic drug substance at a rate of from 2 mg/(kg*h) to 4 mg/(kg*h) and to adjust the estimated or measured non-zero amounts of the anesthetic drug substance based on at least one of the following:
- the electroencephalographic data, activity of the slow waves, and data relating to the estimated or measured non-zero amounts of the anesthetic drug substance;
- determine changes in the activity of the slow waves of the electroencephalographic data with respect to the estimated or measured non-zero amounts of the anesthetic drug substance;
- predict a good neurological recovery of the person if the activity of the slow waves increases by more than 50% relative to the activity of the slow waves prior to the introduction of the anesthetic drug substance and predict a poor neurological recovery of the person if the activity of the slow waves does not increase by more than 50% relative to the activity of the slow waves prior to the introduction of the anesthetic drug substance;
- and
- present result data that represent the changes and that show (i) whether the activity of the slow waves has increased by more than 50% with the introduction of the anesthetic drug substance, thereby indicating the good neurological recovery, or (ii) whether the activity of the slow waves has not increased by more than 50% with the introduction of the anesthetic drug substance, thereby indicating the poor neurological recovery.
A method comprising:
- causing estimated or measured non-zero amounts of an anesthetic drug substance to be introduced continuously into a body of a person at a rate of from 2 mg/(kg*h) to 4 mg/(kg*h);
- receiving electroencephalographic data for a brain based on at least one measurement of the person exposed to the estimated or measured non-zero amounts of the anesthetic drug substance, the electroencephalographic data comprising slow waves having a frequency at or below 1 Hz;
- adjusting the estimated or measured non-zero amounts of the anesthetic drug substance based on at least one of the following:
- the electroencephalographic data, activity of the slow waves, and data relating to the estimated or measured non-zero amounts of the anesthetic drug substance;
- determining changes in the activity of the slow waves of the electroencephalographic data with respect to the estimated or measured non-zero amounts of the anesthetic drug substance;
- predicting a good neurological recovery of the person if the activity of the slow waves increases by more than 50% relative to the activity of the slow waves prior to the introduction of the anesthetic drug substance and predicting a poor neurological recovery of the person if the activity of the slow waves does not increase by more than 50% relative to the activity of the slow waves prior to the introduction of the anesthetic drug substance;
- and
- presenting result data that represent the changes and that show (i) whether the activity of the slow waves has increased by more than 50% with the introduction of the anesthetic drug substance, thereby indicating the good neurological recovery, or (ii) whether the activity of the slow waves has not increased by more than 50% with the introduction of the anesthetic drug substance, thereby indicating the poor neurological recovery.
A non-transitory computer readable medium having a computer program code stored thereon, the computer program code being configured to cause a computer apparatus to:
- cause estimated or measured non-zero amounts of an anesthetic drug substance to be introduced continuously into a body of a person at a rate of from 2 mg/(kg*h) to 4 mg/(kg*h);
- receive electroencephalographic data for a brain based on at least one measurement of the person exposed to the estimated or measured non-zero amounts of the anesthetic drug substance, the electroencephalographic data comprising slow waves having a frequency at or below 1 Hz;
- adjust the estimated or measured non-zero amounts of the anesthetic drug substance based on at least one of the following:
- the electroencephalographic data, activity of the slow waves, and data relating to the estimated or measured non-zero amounts of the anesthetic drug substance;
- determine changes in the activity of the slow waves of the electroencephalographic data with respect to the estimated or measured non-zero amounts of the anesthetic drug substance;
- predict a good neurological recovery of the person if the activity of the slow waves increases by more than 50% relative to the activity of the slow waves prior to the introduction of the anesthetic drug substance and predict a poor neurological recovery of the person if the activity of the slow waves does not increase by more than 50% relative to the activity of the slow waves prior to the introduction of the anesthetic drug substance;
- and
- present result data that represent the changes and that show (i) whether the activity of the slow waves has increased by more than 50% with the introduction of the anesthetic drug substance, thereby indicating the good neurological recovery, or (ii) whether the activity of the slow waves has not increased by more than 50% with the introduction of the anesthetic drug substance, thereby indicating the poor neurological recovery.
Dependencies are inferred from the claim text.