Biosynthesis of everninomicin analogs in Micromonospora carbonacea var aurantiaca

A compound having the structure:

• wherein
• R5-R6 are each, individually, H, OH, OCH3, CH2OH, CHO, CO2H, CO2R12, C(O)R12, or C1-C6 alkyl;
• R7 is H or CH3;
• R8 is H, OCH3, CH2OH, CO2H, CO2R12, C(O)R12, or substituted C1-C6 alkyl that is substituted with alkyl, alkoxy, halide, or hydroxy;
• R9 is H, OH, OCH3, or C1-C6 alkyl;
• each R11 is, independently, H, OCH3, C1-C6 alkyl, or a 1-20 atom linker bound to rosaramicin;
• and
• R12 is C1-C6 alkyl,
• or a pharmaceutically acceptable salt thereof, wherein the compound is not